Rationale: Pulmonary fibrosis is an infamous sequela of coronavirus disease 2019 (COVID-19) pneumonia leading to long-lasting respiratory problems and activity limitations. Pulmonary rehabilitation is beneficial to improve the symptoms of lung fibrosis. We experienced a post-COVID-19 pulmonary fibrosis patient who received a structured exercise-based pulmonary rehabilitation program.Patient concerns: This article presents a case of successful pulmonary rehabilitation of a patient with post-COVID-19 pulmonary fibrosis. The patient could not cut off the oxygen supplement even after a successful recovery from COVID-19. Diagnosis: Diagnosis of COVID-19 was based on the reverse transcription-polymerase chain reaction (RT-PCR). Pulmonary fibrosis was diagnosed by patient's complaint, clinical appearance, and computed tomography (CT) on chest. Intervention: The patient underwent ten sessions of exercise-based rehabilitation program according to Consensus Document on Pulmonary Rehabilitation in Korea, 2015. Outcome: On the 8th day, he could cut off the oxygen supplementation and complete the one-hour exercise without oxygen. He was discharged after completing the 10-session program without any activity limitations. Lessons: Exercise-based pulmonary rehabilitation will help the post-COVID-19 pulmonary fibrosis patients. This case suggested the importance of pulmonary rehabilitation program to the post-COVID-19 pulmonary fibrosis patient. Abbreviations: COVID-19 = coronavirus disease 2019, CT = computed tomography, RPE = rating of perceived exertion, SARS = severe acute respiratory syndrome, SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2.
Since the coronavirus disease 2019 (COVID-19) outbreak, many neurologic and neuromuscular sequelae have been reported [1]. Among these, stroke is the most notorious complication due to the thrombo-inflammatory nature of . For cases that involve the peripheral nerves, Guillain-Barré syndrome Neurologic complications have been reported in patients with coronavirus disease 2019 (COVID-19). Here, we report a case of post-COVID-19 critical illness polyneuropathy and describe the longitudinal follow-up. A 73-year-old woman presented with peripheral muscle weakness following COVID-19 pneumonia and mechanical ventilation for 16 days. Despite treatment, her fever persisted, and oxygen supplementation was continued. Blood cultures revealed Candida albicans infection, prompting antibiotic and antifungal therapy with oxygen supplementation. Two months later, the patient responded to treatment and was extubated. However, she exhibited peripheral muscle weakness. Nerve conduction studies showed peripheral polyneuropathy with axonal involvement, consistent with critical illness polyneuropathy. After 2 months of inpatient rehabilitation, the patient's weakness and activity limitations improved. However, nerve conduction studies taken after 4.5 months showed persistent bilateral lower extremity axonal neuropathy. To the authors' best knowledge, this is the first report of longitudinal follow-up with a functional evaluation of COVID-19-associated critical illness polyneuropathy.
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