Background: Polycystic ovary syndrome (PCOS) is enigma faced by young females since the onset of urbanization. As on day, PCOS is the most common endocrine disorder in the women of reproductive age affecting 4-10%. This study done to measure serum vitamin D3 levels of PCOS patients and to identify its association with factors associated with various symptoms and signs in PCOS.Methods: Institutional based prospective observational study conducted on 70 patients of PCOS, both suspected and already diagnosed, attending gynecology OPD of Department of obstetrics and gynecology of NSCB Medical College Jabalpur from 1 March 2015 to 31 August 2016. Diagnosis of PCOS was made by Rotterdam 2003 criteria. A detailed assessment was done and preformed proforma was filled. Serum Vitamin D3 levels were estimated by standard lab technique ‘Liquid Chromatography Tandem Mass Spectrometry’ and categorized into vitamin D3 sufficient >30ng/dl, insufficient 20-29ng/dl and deficient <20ng/dl. Categorical data was coded numerically before the analysis. For comparison of frequency distribution chi square test or fisher’s exact test were applied as appropriate.Results: Prevalence of Vitamin D3 deficiency in patients of PCOS was found to be 84.3%.Conclusions: The present study concludes that there is correlation between vitamin D3 and PCOS, screening and correction of vitamin D3 deficiency may prevent PCOS and its manifestations. Hence, it is speculated that improvement of vitamin D3 levels at a younger age can contribute to prevention of PCOS.
Oct. 2010. A total of 106 high risk cases meeting the inclusion criteria were subjected to admission CTG testing in this prospective study. Result of admission CTG testing was correlated with perinatal outcome. Results: The admission test had sensitivity of 38.1%, specificity of 100% and positive predictive value of 100% for predicting an Apgar score<5 at birth with diagnostic accuracy of 87.7%. Neonatal admission to neonatal intensive care (NICU) was required in 76.2% of patients with an abnormal test result while only 36.5% of patients with the normal test results were subjected to NICU admission and this was statistically significant ( 2 =10.76; p<0.01). Conclusions:The results suggested that electronic fetal monitoring (CTG) is mandatory in all high risk obstetric cases on admission.
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