Hydrogen sulfide (H2S) acts as a crucial biological and environmental component in a variety of processes. Abnormal levels of H2S endogenously generated in human body are associated with various diseases. Meanwhile, H2S gas leaked from various manufacturing environments has a fatal effect against the human body. For this reason, H2S has been considered as a potential biomarker for the diagnosis and treatment of various human diseases, and as a toxic gas that should be detected when leaked to the workplace for the safety of workers. In this study, we synthesized an azide‐containing naphthalimide derivative that can play as a fluorescence turn‐on probe for H2S.
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