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Pimecrolimus is an ascomycin derivative and belongs to the family of calcineurin inhibitors. Its mechanism of action is the blockage of T-cell activation. In contrast with topical steroids, pimecrolimus is not thought to induce skin atrophy with prolonged use. 8 Our patient was successfully managed with topical 0.1% pimecrolimus and adequate sun protection. He remains free of recurrence over a period of 24 months of follow-up. Although topical 0.1% pimecrolimus has been successfully used for the treatment of mucosal lichen planus, 9 its use in the management of actinic lichen planus has not been investigated so far. We postulate that topical 0.1% pimecrolimus could be useful in the treatment of ALP.

Venous malformations of the skin and subcutaneous tissue are compressible, blue-purple tumors that are present at birth. According to the location and symptoms caused, venous malformations can be treated with surgery, sclerotherapy, or a combination of both. Laser therapy can also be used, especially when surgery is contraindicated. We report the case of a 24-year-old man who presented with a venous malformation on the upper and lower left eyelids, which provoked a mechanical ptosis. Treatment with sequential pulsed-dye neodymium yttrium aluminum garnet (PDL-Nd:YAG) laser was performed. After 2 treatments, a marked reduction of volume and blanching of the venous malformation was observed, with satisfactory cosmetic results. The sequential PDL-Nd:YAG laser seems to be an effective and safe therapy for the treatment of cutaneous venous malformations. It penetrates deeper than pulsed-dye laser alone, and because it allows the use of lower fluencies than Nd:YAG laser alone, it reduces the risk of adverse effects.

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