Oral cancer results due to multiple genetic alterations that transform the normal cells in the oral cavity into neoplastic cells. These genetic changes in a particular tumor field lead to a rapid expansion of preneoplastic daughter cells producing malignant phenotype but the malignancy results due to such genetic changes occurr over several years. The morphological changes in these transformed cells help in the diagnosis of malignancy. Thus, the early changes at the gene level are present in the population of daughter cells in the organ, which explains the concept of field cancerization. Cancer stem cells (CSCs) represent a group of cells that have the capacity of self-renewal and have the potential to differentiate into other types of tumor cells. This review explains the cellular and genetic basis of field cancerization and the role of cancer stem cells in field cancerization.

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SUMMARY :Animal husbandry has been regarded as subsidiary occupation by the farmers of our country. Despite of the fects that we are having a large population of animals, the milk food is very low to augment the milk production of country of cross breeding with Exotic breeds have been extended on a massive scale, milk production cannot be increase only having cross bread animals but the farmers must be trained in proper reading of these animals. As per the principle of extension due consideration be given to the felt heeds of the farmers must be trained as per their requirement in various aspects of rearing cross-bred animals. With this consideration present investigation entitled "Study of training heed of farmers in Sambhar Lake Panchayat Samiti (Jaipur-Rajasthan) with special reference to rearing cross bred animals. To get right need and provided opportunities is the surest way to contribute to economic growth and overall development for rearing cross-bread farmers."How to cite this article : Aloria, Om Prakash, Sharma , S.K. and Sivasiya, Manju Devi (2017). To determine future training requirements of the farmers about rearing cross-bred animals on the basis of subject matter areas of training.

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