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BACKGROUND Dimorphic anaemia is very common in India. Dimorphism indicates the presence of two distinct populations of red cells. The term is most often applied when there is one population of hypochromic, microcytic cells and another population of normochromic cells, either normocytic or macrocytic. Aims and Objectives-1. Dimorphic anaemia has been studied, because treatment may be ineffective if the dual deficiency is not diagnosed. 2. To correlate and compare the clinico-haematological, biochemical parameters with bone marrow study. 3. To find out the clinical and haematological features of severe anaemia with bone marrow study. MATERIALS AND METHODS This descriptive study included 51 cases of dimorphic anaemia to evaluate association of biochemical profile of dimorphic anaemia with bone marrow study. Data collected from case files, patient history, clinical profile, peripheral blood findings, haematological parameters, bone marrow aspiration and biochemical parameters. RESULTS In our study, dimorphic anaemia (DA) was mostly found in 15-30 years of age. The male-to-female ratio was 1.5: 1 in our study. The most common clinical presentation was pallor and generalised weakness (100%) followed by easy fatigability (72.5%), fever (54.90%), altered behaviour (19.6%) and tingling (8%) are found. Bleeding (13.7%), itching and red spots (13.7%) are found in patients having thrombocytopenia. DA was found mostly in vegetarians (62.7%). The mean haemoglobin was 6.6 gm/dL. Splenomegaly and hepatomegaly were present in 35.2% and 23.5% respectively. There was complete correlation between three parameters in 8/51 (15.68%) cases only. CONCLUSION Bone marrow examination provides rapid and cost-effective investigation for confirming the diagnosis of dimorphic anaemia by reliably assessing the iron stores. Serum ferritin is more specific in predicting the iron deficiency. Serum vitamin B12 and serum folate are also specific, but not sensitive.

Introduction: ABO blood group was discovered by Landsteiner in 1900. ABO and Rhesus blood group antigens are important in transfusion medicine and its incidence differ in races, ethnic groups and socioeconomic groups. Material and Methods: This retrospective study was conducted in blood bank of district hospital associated with government medical college, Khandwa during 6-months period between 1 January 2019 to 30 June 2019. 3300 individuals were considered fit for donating blood. Age range between 18 and 60 years. The donors who's haemoglobin more than 12.5 gm% were selected and screened by medical officer. ABO and Rhesus blood groups were determined by slide test and tube method. Results: The common age group for blood donation was 21-30 years. Out of 3300 donors, 98% were males and 2% were female. The commonest blood group was B (33.91%) followed by O (29.12%), A (26.78%), AB (10.29%). ABO blood group pattern in decreasing order was B > O > A > AB. Rh-positive donors were 95.3% and Rh negative were 4.7 %. Conclusion:This Blood group study will be helpful in health care planning, running of organized, efficient and safe blood transfusion services.

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