Lewis acid-catalyzed alpha-amidoalkylation of enolizable aldehydes with N-(alpha-benzotriazolyl-alpha-arylalkyl)amides followed by intramolecular Friedel-Crafts cyclization provides a convenient route to 2-substituted 1-amidoindenes.

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ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.