Aim: The aim of the study was to investigate the restoration of metabolic imbalance related with deficiency of insulin by the exogenous androgen supplementation in the experimental model of alloxan-induced diabetes in Wistar male rats. Methods: The experimental diabetes was induced by a single intraperitoneal administration of alloxan. The concentrations of glucose, immunereactive insulin, corticosterone, testosterone and estradiol were examined in blood, the intensity of DNA and RNA synthesis and androgen receptor expression were studied in the liver Results:The induction of diabetes increased the concentrations of glucose, corticosterone and estradiol while decreases insulin and testosterone concentration in blood as well as DNA/RNA synthesis and androgen receptors expression in hepatocytes. The administration of exogenous androgen significantly restored the metabolic imbalance and the expression of androgen receptors and increased DNA/RNA synthesis in liver cells maintained close to control level. Conclusion: The administration of methyltrienolone reduced the effect of "diabetic stress" and restored the hormonal dysfunction induced by alloxan.

Rubrene was doped into the hole transport layer of an organic thin film electroluminescent (OTFEL) device with a double-layered structure. It was found that the dopant has a profound influence on the EL characteristics-it changed the region of light emission, increased the luminescence efficiency by more than 50% and improved the device stability tenfold. The reasons for these effects are discussed based on injection theory and the energy level diagram of the device.

A nondestructive refractometric method for determining the concentration distribution of a diffusing material into a light focusing polymer gradient elements (LFPGE) is developed.