The field sensitivity of a planar Hall effect (PHE) micro-ring type biosensor has been investigated as a function of magnetizing angle of the sensor material, for the sensing of low magnetic moment superparamagnetic labels. The field sensitivity is maximal at a magnetizing angle of α = 20°. At this optimized magnetizing angle, the field sensitivity of a PHE sensor is about 3.6 times higher than that measured at the conventional configuration, α = 90°. This optimization enables the PHE-ring sensor to detect superparamagnetic biolabels with ultra-low magnetic moments down to 4 × 10−13 emu.