BackgroundMalaria transmission in Mali is seasonal and peaks at the end of the rainy season in October. This study assessed the seasonal variations in the epidemiology of malaria among children under 10 years of age living in two villages in Selingué: Carrière, located along the Sankarani River but distant from the hydroelectric dam, and Binko, near irrigated rice fields, close to the dam. The aim of this study was to provide baseline data, seasonal pattern and age distribution of malaria incidence in two sites situated close to a lake in Selingué.MethodsGeographically, Selingué area is located in the basin of Sakanrani and belongs to the district of Yanfolila in the third administrative region of Mali, Sikasso. Two cross-sectional surveys were conducted in October 2010 (end of transmission season) and in July 2011 (beginning of transmission season) to determine the point prevalence of asymptomatic parasitaemia, and anaemia among the children. Cumulative incidence of malaria per month was determined in a cohort of 549 children through active and passive case detection from November 2010 through October 2011. The number of clinical episodes per year was determined among the children in the cohort. Logistic regression was used to determine risk factors for malaria.ResultsThe prevalence of malaria parasitaemia varied significantly between villages with a strong seasonality in Carrière (52.0–18.9 % in October 2010 and July 2011, respectively) compared with Binko (29.8–23.8 % in October 2010 and July 2011, respectively). Children 6–9 years old were at least twice more likely to carry parasites than children up to 5 years old. For malaria incidence, 64.8–71.9 % of all children experienced at least one episode of clinical malaria in Binko and Carrière, respectively. The peak incidence was observed between August and October (end of the rainy season), but the incidence remained high until December. Surprisingly, the risk of clinical malaria was two- to nine-fold higher among children 5–9 years old compared to younger children.ConclusionsA shift in the peak of clinical episodes from children under 5–9 years of age calls for expanding control interventions, such as seasonal malaria chemoprophylaxis targeting the peak transmission months.
The fundamental problem of similarity studies, in the frame of data-mining, is to examine and detect similar items in articles, papers, and books with huge sizes. In this paper, we are interested in the probabilistic, and the statistical and the algorithmic aspects in studies of texts. We will be using the approach of k-shinglings, a k-shingling being defined as a sequence of k consecutive characters that are extracted from a text (k ≥ 1). The main stake in this field is to find accurate and quick algorithms to compute the similarity in short times. This will be achieved in using approximation methods. The first approximation method is statistical and, is based on the theorem of Glivenko-Cantelli. The second is the banding technique. And the third concerns a modification of the algorithm proposed by Rajaraman et al. ([1]), denoted here as (RUM). The Jaccard index is the one being used in this paper. We finally illustrate these results of the paper on the four Gospels. The results are very conclusive.
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