Sickle cell disease is a genetic disease with autosomal recessive transmission due to the presence in the red blood cell of abnormal hemoglobin called hemoglobin S. It would be the most widespread hemoglobinopathy in the world affecting nearly 120 million people according to the WHO. This disease is very frequent in Africa south of Sahara, where in Senegal it affects almost 10% of the population. It is responsible for polymorphic clinical manifestations, in particular ophthalmologic. However, the latter are very little described by the literature in our country. We report our experience of ocular lesions found in heterozygous sickle cell subjects monitored in our department.

The cases of hypermetropia in patients aged 5 to 40 years were studied at Aristide Le Dantec hospital in Dakar. There are 85 patients including 28 men and 57 women. The average age was 22 years old. Headache was the most common reason for consultation (79.69%). The average consultation time was 6 days after onset of functional symptoms. Complications were strabismus (21.88%) and amblyopia (3.12%). A negative impact on the socio-professional level was noted in 60.94%. The treatment consisted of an optical correction by glasses in 96.87%.

In the Article the main sources of danger in the operation of technological equipment are considered. The main sources of hazards have been identified -this is the problem of the emergence and development of a thermal explosion during the operation of technological equipment and storage facilities. The basic conditions for the analysis of the occurrence and development of a thermal explosion are derived based on an analysis of the equations of thermal and material balance in reactors and other equipment, where exothermic reactions can occur.Equations are obtained for a different mechanism of heat energy transfer, due to conduction, and convection, both forced and natural. The basics of numerical methods for solving the corresponding equations in partial derivatives are considered.