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Citation: Shopov S. А collision between fibroma and serous ovarian cystadenoma mimicking carcinoma. Folia Med (Plovdiv) 2019;61(4):634-8. AbstractCollision tumors represent a coexistence of two adjacent but histologically distinct tumors without histologic admixture in an organ.Ovarian fibroma is the most common benign stromal tumor. Serous tumors of the ovary are the most common of epithelial tumors. However, a collision between them is a rare pathology mimicking a malignant tumor. We report a 63-year-old woman with sparse postmenopausal bleeding. Ultrasound examination of organs in a small pelvis rounded right ovary formation with hypo and hyperdense sections. Paraclinical: CA125 slightly increased. Histological: collision between two benign ovarian tumors imitating carcinoma.

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Large-cell neuroendocrine carcinoma of the endometrium is an insufficiently researched aggressive tumor with a short survival regard­less of the treatment type. We present here the 38th consecutive case of literature reported cases of large cell neuroendocrine carcinoma of the endometrium (posi­tive for synaptophysin, CD56, chromogranin A, p53, and Vimentin) found in the myomatous uterus of a 76-year-old woman. We also describe in the study the morphological algorithm for differentiation of malignant blastomas with small (under 10 %) neuro-endocrinal component. Accumulated clinical and morphological evidence raises the question whether the large-cell and the small-cell neuroendocrine carcino­mas are just different variations according to their histology and topical occurrence (uterine body/cervix) or they are just independent forms with their respective clinical signs, morphology, treatment, and prognosis.

Perianal and perineal pruritus is often associated with Enterobius vermicularis in children. Although this roundworm is common in pediatric practice, most doctors are unaware that it can cause appendicular colic with/or appendicitis, severe urogenital complications, bowel perforation, and peritonitis. We report a case of a young male who presented with signs and symptoms of acute peritonitis. Dur-ing the operation, perforation of the jejunum with a purulent exudate under the transverse colon, a left lateral canal, a Douglas cavity were found as well as single enlarged mesenteric lymph nodes. Histological studies detected Enterobius vermicularis in the lumen of the appendix and jejunum, as well as in the purulent exudate in the intestinal wall and serosa. A mesenteric lymph node, histologically presented with chronic nonspecific lymphadenitis. In conclusion, infection with Enterobius vermicularis should be considered in peri-tonitis, appendicitis, and enlarged mesenteric lymph nodes, especially in young patients.