European Journal of Trauma Ab stractBackground: Degloving is a potentially serious injury in which an extensive area of skin is torn from its underlying attachments and thereby deprived of its blood supply. Case Study: Two cases of degloving injury are described, one occurring as a result of the shearing effect of a vehicle wheel passing over the limb in a run-over accident and one caused by a ring of the fourth-hand finger. The degloved skin must be grafted with the help of plastic surgery either by removing the subcutaneous fat from the damaged skin and applying it as a free graft or by taking a graft from elsewhere. Conclusion: Degloved skin is dead and should be replaced as if it were a free skin graft. A number of plastic surgical procedures are available at the moment. IntroductionDegloving injuries cause stripping of skin and underlying tissues from the bones, usually of the hands or feet, as occurs in run-over accidents, wringer or industrial roller injuries [3,22,46,48]. These two cases of degloving injury of the lower limb and the fourth finger of the right hand, respectively, are presented in order to describe this rare and potentially very serious injury of soft tissue.