Image denoising and segmentation are required to use in digital image processing. For researchers' point of view, still, these two methods are challenging task in medical images. At present, image denoising and segmentation take part in real-world applications such as computer graphic, computer vision, satellite, and medical fields. These two methods are analyzed by using different images but mainly concentration on medical images such as computed tomography, single photon emission computed tomography, magnetic resonance imaging, positron emission tomography. Medical images can break into noise, major research has created solutions to this complication, various techniques are being proposed. Image segmentation is a widespread and active area not only for medical imaging but also for computer vision and satellite imaging. The foremost plan of image segmentation remains to segment images into different components, which are used to give more information about the medical image. Here is an overview of the different methods after a brief introduction. These methods are classified as the basis for the techniques used. Index Terms-Image denoising, Image segmentation, performance parameters, derivative based image denoising, clustering methods. I. INTRODUCTION Digital image processing requires a computer to work with images, so it is fit aimed at image investigation, pattern recognition, together with human reflection. By means of computer knowledge, digital image processing has several applications over different industries such as face recognition, medical imaging, computer vision, remote sensing, and medical sciences. Medical images such as computed tomography, single photon emission computed tomography, magnetic resonance imaging, positron emission tomography contains rich information, both anatomy, and functionality that can be used to diagnose, plan, and investigate operations. These images can be either a two-dimensional image or a three-dimensional image, which is solved in terms of both time and non-time. A large amount of information on these pictures can be evaluated with simple visualization, but for quantitative measurements, the object must be divided into segments. Possible quantitative measurements such as organs size, heart infarct size, muscle weakness, tumor size, as well as tumor Manuscript