OBJECTIVE: Many studies confirm that psychological factors and burnout in physicians are interconnected. It is however not known, whether quality of life is another factor that plays a role in this connection.The aim of this study was to explore the correlation between quality of life and emotional profile with the level of burnout in physicians. PARTICIPANTS: 120 physicians participated in this study, i.e. sixty general practitioners (GPs) and sixty psychiatrists. METHODS:The General Health Questionnaire (GHQ) and the Maslach Burnout Inventory (MBI) were used to measure the job stress. The Quality of Life (QOL) and the Emotions Profile Index (EPI) were used to determine quality of life and emotional profile. Data were analyzed using methods of single and multiple correlation and regression methods. RESULTS: The QOL was higher in psychiatrists as a direct consequence of questions about finances and friendship. Analysis by gender showed that the growth of the burnout risk level (MBI) correlated with the growth of number of women who had stress coping problems. CONCLUSIONS: This research suggests that quality of life and individual factors represent a very significant role in burnout among physicians. Further researches in a bigger sample are required in order to identify key factors of quality of life related to burnout reducing, as well as for improvement of supervision strategies, including more the relevance of psychological profile of physicians.

Gray-level co-occurrence matrix (GLCM) analysis is a contemporary and innovative computational method for the assessment of textural patterns, applicable in almost any area of microscopy. The aim of our research was to perform the GLCM analysis of cell nuclei in Saccharomyces cerevisiae yeast cells after the induction of sublethal cell damage with ethyl alcohol, and to evaluate the performance of various machine learning (ML) models regarding their ability to separate damaged from intact cells. For each cell nucleus, five GLCM parameters were calculated: angular second moment, inverse difference moment, GLCM contrast, GLCM correlation, and textural variance. Based on the obtained GLCM data, we applied three ML approaches: neural network, random trees, and binomial logistic regression. Statistically significant differences in GLCM features were observed between treated and untreated cells. The multilayer perceptron neural network had the highest classification accuracy. The model also showed a relatively high level of sensitivity and specificity, as well as an excellent discriminatory power in the separation of treated from untreated cells. To the best of our knowledge, this is the first study to demonstrate that it is possible to create a relatively sensitive GLCM-based ML model for the detection of alcohol-induced damage in Saccharomyces cerevisiae cell nuclei.

The obtained results showed a high burnout risk level in both, GPs and psychiatrists, groups. In both groups there was no presence of psychic disorders (anxiety, depression, insomnia), while there was a high level of emotional ehausation and overtension by job, and also a lower total personal accomplishment. Level of exposition to professional stress is higher in GPs than in psychiatrists, but the difference was not statistically significant.

Introduction/objective: The burnout syndrome is insufficiently investigated within the population of students. The aim of this study was to determine the level of burnout in medical students of medicine in Belgrade with the emphasis on preclinical/clinical differences, as well as differences according to gender and average grade. Methods: The Maslach Burnout Inventory Student Survey (MBI SS) was used to conduct the research among the students of medicine, consisting of emotional exhaustion subscale (MBI-EE), cynicism subscale (MBI CY) and academic efficiency subscale (MBI EF). Results: High level of burnout according to the MBI EE of the entire sample was confirmed in 84.4 % of students; medium level of burnout according to the MBI CY in 40.7 % and high in 31.7 %. According to the MBI EF, 61.2 % of the students had a medium and 16.9 % high level of burnout. The MBI EE and MBI EF scores were significantly higher in first year students, while the MBI CY score was higher with fifth year students (p<0.01). No gender difference was detected (p > 0.05) nor was the difference between the students with higher and lower average grade (p > 0.05) detected. Conclusion: The high burnout level in this study indicates the need for research on a larger sample, aiming at preserving the health of the future medical practitioners. It also causes concern about high scores especially in the preclinical, as well as in the clinical academic years.

Fenomen stresa je komplikovan i sadrži različite definicije. Prve studije o stresu su se zasnivale na fiziologiji, ali su se sredinom prošlog veka pojavili i mnogi psihološki modeli. Reakcija na stres može da nastane ne samo kao reakcija na stvarne psihološke i fizičke događaje, nego i u njihovom očekivanju. Ovaj tip stresa se naziva "psihološki" i smatra se najvažnijim u današnjem društvu kao glavni razlog hroničnog stresa. Profesionalni, radni ili stres vezan za profesiju, ima relativno kratku istoriju u naučnom razmatranju. Određene teorije ističu interakciju osobe i sredine. U poslednjih nekoliko godina pritisak na lekare porastao je u mnogim zemljama, kao rezultat različitih reformi zdravstvene zaštite koji utiču na autonomiju lekara, prestiž i prihode, što dovodi do većeg stresa na radu. Radni stres može dovesti do hroničnih reakcija, kao što su loše zdravlje, iscrpljenost i depresija. Cilj ovog istraživanja bio je ispitivanje i utvrđivanje nivoa profesionalnog stresa kod lekara urgentne medicine i psihijatara, kao i faktora koji utiču na njegov nastanak, razvoj i ispoljavanja (koja se u savremenoj medicinskoj literaturi označavaju kao tzv. "sindroma izgaranja" , odnosno "burnout sindrom" ili jednostavno "burnout", a "burnout" na engleskom znači sagorevanje ili izgaranje i kod nas se kao termin često koristi u stručnim krugovima) Istraživanje je koncipirano kao studija preseka. Ispitanici su bili lekari psihijatri i lekari urgentne medicine (prosečan broj radnih sati kod svih je bio veći od 35 nedeljno), i podeljeno je 330 upitnika. Ukupan broj popunjenih testova je bio 302 (152 lekara urgentne medicine i 150 psihijatara), što daje veoma visok procenat odgovora od 91,8%. Ispitivanje je urađeno pomoću upitnika koji se sastojao od šest celina i to: Sociodemografski upitnik, Opšti zdravstveni upitnik (General Health Questionairre-GHQ), Masleč inventar izgaranja (Maslach Burnout Inventory-MBI), Kvalitet života (Quality Of Life-QOL), Upitnik o zadovoljstvu zaposlenih (UZZ) i Profil indeks emocija-PIE (Emotions Profile Index). Nivo "burnout"-a (MBI) bio je u sva tri domena viši nego u sličnim studijama u svetskoj literaturi, kao i nivo psihičkog distresa (GHQ), a isti skorovi su takođe bili viši od onih u poznatim, do sada publikovanim i/ili realizovanim radovima u našoj zemlji. Kvalitet života (QOL) i zadovoljstvo zaposlenih poslom (UZZ) u ovom uzorku, statistički značajno su korelirali sa gore navedenim nalazom "burnout"-a i psihičkog distresa. Takođe je bio komplementaran nalaz određenih karakteristika emocionalnog profila ispitanika (PIE), i pokazao je uticaj i značaj unutrašnjih faktora na ukupnu percepciju profesionalnog stresa. Brak, godine, pol i navike bile su sociodemografske karakteristike značajno statistički povezane sa navedenim faktorima. Opšti zaključak je da je nivo profesionalnog stresa kod lekara urgentne medicine i psihijatara u ovom istraživanju bio visok, a kao faktori koji utiču i doprinose njegovom nastanku, održavanju i posledicama, dokazani su nivo "burnout"-a, psihički distres, kvalitet...