Introduction: As diabetes mellitus is one of the most challenging public health problem in 21st century, it is important to know about the awareness level of a disease condition in a population, which plays a vital role in future development, early detection and prevention of disease. Objective: To assess the awareness and knowledge regarding diabetes mellitus among diabetic and non-diabetic subjects. Methods: A prospective and observational study was done in 100 diabetic and 50 non-diabetic subjects. All in-patients and outpatients either gender, of age 20-80 years were included in the study. Paediatric patients, pregnant/lactating women were excluded. Result: After analysing the scores, it was found that among diabetic patients 46% had poor knowledge, 45% had medium knowledge and 9% had good knowledge regarding Diabetes Mellitus where as 64% of non-diabetics had poor knowledge, 34% of non-diabetics had medium knowledge and 2% of non-diabetics had good knowledge regarding Diabetes Mellitus. Conclusion: Overall, our study concludes that diabetic patients had more knowledge regarding diabetes mellitus than non-diabetic subjects.

A prospective observational study was conducted at Bhimavaram hospitals Bhimavaram, to assess the symptoms, risk factors and prescribing patterns in cerebral stroke patients. A total of 80 patients of age group 20-90 (mean age 63.1) were considered in the study which includes both the genders. These patients were assessed regarding their demographics, symptoms, risk factors and prescribing patterns. The incidence of stroke was higher in males (70%) compared to females (30%). Out of these study population 85% experienced Ischemic stroke, 11% Transient ischemic attack (TIA) and 4% Hemorrhagic stroke. These patients presented weakness as common symptom, Hypertension as prominent risk factor and anti-platelet agents as commonly prescribed drugs. Early management of Hypertension and Diabetes may reduce the risk of stroke. Our study suggests that life style changes play a key role in prevention of stroke.

A677100. Results: There were 344 falls including 142 cases (41.3%) with CNDs administration, and the duration of prescription were 62,622 prescription-days. From the viewpoint of length of drug effectiveness, Fall rate for CNDs were 0.16% in short-acting CNDs, 0.25% in intermediate-acting CNDs, and 0.26% in long-acting CNDs. ConClusions: This result suggested that long-acting CNDs were strongly related with falls. To prevent falls within a hospital, hospital personnel including nursing staff have to be educated about CNDs.

In healthcare delivery system, medicines play a key role in reducing patient's suffering. Nonetheless, irrational use of medicines remains a major issue facing most health systems across the world. This might eventually lead to drug interactions and adverse drug reactions (ADRs). Hence a study was planned with an aim to evaluate the prevalence of drug interactions and adverse drug reactions in a tertiary care hospital. A total of 500 patients were selected by convenience sampling method. Complete case records of all the 500 subjects were collected. 26.32% (n = 15) ADRs are seen in the age group of 51-60 years. 70.18% (n = 40) of ADRs are seen in males. Irrational prescribing is seen in 30.2%. Most of the (Potential Drug Drug Interactions) PDDIs are due to the combined use of aspirin and clopidogrel (n = 76). Hence, by evidence based practice and rational drug use guidelines, the adverse drug effects can be minimized. Also, by minimizing polypharmacy the number of ADRs can be reduced, thereby decreasing the cost of health care.

One of the important fundamental human rights is access to health care. Various governments have shown international agreements about this right. Disease management and prevention is mainly through drugs. Complete information about the drugs is given in World Health Organization (WHO) formularies. Aim of the study was to develop a hospital formulary in a tertiary care hospital. Drug list comprising of 450 drugs was collected from hospital pharmacy. After scrutinizing the list for unutilized and banned drugs, a total of 423 drugs were selected to prepare monographs for hospital formulary. The hospital formulary book was distributed to the doctors, nursing staff and pharmacy to avoid medication administrative errors and also to provide ease of reference. The formulary was also designed in a way to help the patients receive drugs economically by including the high quality drugs of affordable brands. Results showed that fixed dose combinations accounts for highest percentage of drugs in Varma hospital formulary i.e., 22.22% (n=94) whereas it is only 8.19% (n=28) in National formulary of India whereas blood products accounts least i.e., 1.89% (n=8) in Varma hospital formulary and 1.46% (n=5) in National formulary of India. Development of hospital formulary system helps in reducing the number of brands for the same drug, selecting the drugs at affordable cost with superior quality. On a whole, the formulary helps in providing quality treatment to the patient in a standardized way.