A 17-lump kinetic model has been developed for the riser-reactor cum regenerator of a fluid catalytic cracking unit (FCCU). This accounts for cracking, hydrogen transfer, aromatization, isomerization, alkylation and dimerization, as well as catalyst deactivation due to the coke deposition in its pores. A model for the industrial combustor-regenerator unit is also developed. The lumping scheme includes the detailed characterization in terms of the paraffins, naphthenes and aromatics (PNAs) for the VGO feed and also the detailed compositions of the two important products: gasoline and LPG. A total of 199 kinetic parameters for the riserreactor cum regenerator have been fitted (tuned) using 192 sets of plant data (under different operating conditions) from an industrial FCC unit. The tuned model of the integrated FCCU was run for 15 additional operating conditions. The match was found to be quite good.

The expression of genes is altered in various diseases and is responsible for the disease's initiation, progression and pathology. Several other genes, predominantly inactivated, may become activated in a given condition and contribute to the initiation and progression of the disease. Similarly, human endogenous viruses (HERVs) are an incomplete, non-productive and inactive viral sequence present in the heterochromatin of the human genome, and are often referred to as junk DNA. HERVs were inserted into the host genome millions of years ago. However, they were silenced due to multiple mutations and recombination that occurred over time. However, their expression is increased in cancers due to either epigenetic or transcriptional dysregulation. Some of the HERVs having intact open reading frames have been reported to express virus-like particles, functional peptides and proteins involved in tumorigenesis. To summarize, there is involvement of different HERVs in the initiation and progression of several cancers. The present review aims to provide concise information on HERV and its involvement in the initiation and progression of multiple types of cancer.

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