No abstract

This study examined the impact of maternal cocaine use and associated risk factors such as polysubstance use, maternal functioning, and caregiving on affect regulation during infancy. Participants were 45 mother‐infant dyads (19 cocaine exposed and 26 control infants) recruited at birth. Observations and maternal reports of infant behavior were obtained at 2 and 7 months of age, along with measures of pre‐ and postnatal substance use, maternal functioning, and caregiving stability. Maternal cocaine use accounted for significant variance in infant positive affect at 2 months. Other substance use and gestational age predicted infant distress to novelty and arousal during developmental assessments. At 7 months, the impact of prenatal cocaine exposure on infant affect regulation was mediated by postnatal alcohol use and caregiving stability. These findings, if replicated, suggest that 1 pathway to later problem behavior reported among substance‐exposed children may be through early regulatory problems and the quality of postnatal caregiving.

The development of motor asymmetries was assessed in 20 infants who were prenatally exposed to cocaine and 23 comparison infants. Asymmetries in stepping, grasping, and head orientation were assessed at 1 month of age. As expected based on the findings of previous research with high-risk infants, infants who were prenatally exposed to cocaine performed a grasping task with their right hand for significantly shorter durations than comparison infants and were less likely to show a dominant hand preference than comparison infants. Comparison infants were also more likely to display a side bias for head orientation and stepping than infants who were prenatally exposed to cocaine. These findings suggest that prenatal exposure to cocaine may alter the typical developmental trajectory of functional asymmetries and may have important implications for long-term developmental outcomes.