Permian large-scale transcurrent tectonics and massive magmatism are prominent features of the Tianshan belt and neighboring regions of the Central Asian Orogenic Belt. Structural, geochronological and geochemical analyses of Carboniferous and Permian intrusive rocks associated with the Kangguer-Huangshan Shear Zone (eastern Chinese North Tianshan) provide constraints on their tectonic setting and the tectonic evolution of the Tianshan belt as well. Carboniferous granitic rocks were emplaced at 338 ؎ 4 Ma and 347 ؎ 2 Ma, respectively, and show geochemical features typical of the calc-alkaline series. These arc-type granites do not display ductile deformation, probably because they were completely cooled at the time of shearing tectonics, and are only offset by brittle strike-slip faults. In contrast, Permian granitoids display pervasive ductile tectonic features diagnostic of synkinematic emplacement. Four gabbro and diorite samples from the East Huangshan intrusive complex yielded zircon U-Pb ages of 267 to 275 Ma, and a granitic dike is dated at 290 ؎ 1 Ma. The granitic dike is cut by en-echelon right-lateral strike-slip faults, and the mafic intrusive complex displays a sigmoidal shape with mylonitic foliation localized at its margins. Other specific pluton shapes (such as tongue and tadpole-like) and synmagmatic deformation can be observed in intrusions of the same age, showing similar fabrics and kinematics consistent with that of the Kangguer-Huangshan Shear Zone. Numerous mafic to felsic dikes occur within and off the shear zone with a dominant SE-NW orientation and minor varieties in N-S or NNE-SSW directions.One gabbro dike that intrudes the early Carboniferous granite of the East Kanggurtag area yielded a magmatic age of 274 ؎ 4 Ma, and contains older zircons (ϳ340 Ma, ϳ390 Ma, ϳ450 Ma, and 1.3-2.2 Ga) probably inherited from intruded rocks. The Permian intrusive rocks have variable chemical compositions suggesting derivation of these rocks from depleted and undepleted (or enriched) mantle sources with involvement of subductionrelated components. We conclude from our integrated analysis of the geological, structural, geochemical and geochronological data that the Permian magmatic rocks were formed in a post-collisional/post-orogenic setting from multiple sources, and were emplaced under the control of large-scale dextral transcurrent tectonics.

a b s t r a c tWhilst petrology, geochemistry and metal content of small mafic/ultramafic Ni-Cu bearing complexes have been extensively studied, their structural controls and emplacement mechanisms are still poorly documented. This study addresses the last two points with the Huangshan Ni-Cu ore belt (Chinese Eastern Tianshan) as a case study. The Huangshan intrusions are Early Permian; a period when the Tianshan orogenic belt recorded major right-lateral wrench tectonics, characterized by crustal-scale shear zones. Detailed mapping, petro-structural analysis and strain rate calculation within and around the intrusions allow us to establish that the Huangshan Ni-Cu-bearing mafic/ultramafic complexes are not layered intrusions. Instead, they emplaced by injection of several mafic/ultramafic magma batches within kilometre-scale tension gashes generated by Permian dextral shearing, and should be considered as synkinematic sheeted intrusions. Finite strain analysis across the Huangshan-Kangguer shear zone provides rather high shear strain rates (4.5). Considering the location and alignment of the Ni-Cu-bearing mafic/ultramafic bodies along regional shear zones throughout Eastern Tianshan, it appears that wrench tectonics most likely controlled and focussed the intrusion of parent magmas. As a consequence, rifting related to post-orogenic extension is not required to account for Permian magmatic features of the Tianshan Belt. Finally, the Huangshan Ni-Cu bearing mafic/ultramafic intrusions are neither parts of an ophiolitic suture, nor of a dunite-cored Alaskan-type ore deposit, as postulated in some previous studies. In the light of these new results, we believe that structural controls and emplacement mechanisms of many NiCu sulphides deposits hosted by small intrusions (particularly funnel-shaped ones) should be (re-)evaluated from a structural and geophysical point of view.

The aim of this study was to provide information about the biological properties of iron oxide nanoparticles (IO-NPs) obtained in an aqueous suspension. The IO-NPs were characterized by transmission electron microscopy (TEM). Analysis of hysteresis loops data at room temperature for magnetic IO-NPs sample indicated that the IO-NPs were superparamagnetic at room temperature. The calculated saturation magnetization for magnetic iron oxide wasMs= 18.1 emu/g. The antimicrobial activity of the obtained PMC-NPs was tested against Gram-negative (Pseudomonas aeruginosa1397,Escherichia coliATCC 25922), Gram-positive (Enterococcus faecalisATCC 29212,Bacillus subtilisIC 12488) bacterial as well as fungal (Candida krusei963) strains. The obtained results suggested that the antimicrobial activity of IO-NPs is dependent on the metallic ions concentrations and on the microbial growth state, either planktonic or adherent. The obtained IO-NPs exhibited no cytotoxic effect on HeLa cells at the active antimicrobial concentrations.