No abstract

Ninety-two cases of persistent corneal erosions in dogs were analyzed for breed, gender, age and which eye was affected. The results of the treatment of 92 persistent corneal erosions in dogs by superficial keratectomy (SK), grid keratotomy (GK), or debridement with a sterile dry cotton swab are presented. These techniques gave better rates of healing than have been previously reported. All cases of persistent corneal erosions healed in this study. However, it must be noted that three cases treated with debridement only failed to heal after several treatments and were eventually treated with SK. After one procedure 80 out of 92 (87%) had healed. After one procedure, 63% of cases treated with debridement healed, 100% of cases treated with SK healed, and 85% of cases treated with GK healed. At the first postoperative visit, 88% (21/24 cases) of ulcers treated by SK had healed, and 75% (39/52 cases) of ulcers treated by GK had healed. Only 25% of the persistent corneal erosions had healed at the first visit after debridement. All 24 cases of persistent corneal erosions treated with SK healed after one treatment in a mean +/- SD of 9.3 +/- 3.9 days (median of 7 days). Fifty-two cases were managed with GK; 44 (83%) of these healed with one procedure and eight cases required a second GK procedure to resolve. A mean +/- SD of 13.4 +/- 5.1 days (median of 11.5 days) following GK was required for the persistent corneal erosions to heal. Nineteen cases were initially managed by debridement with a dry cotton swab under local anesthesia. Sixteen out of these 19 debridement cases healed (giving an overall healing rate of 84%) in a mean +/- SD time of 23.4 +/- 11.1 days (median 21.5). There were three cases that did not heal with debridement. These cases were debrided at 10-20 day intervals for 30-60 days, and were then treated with SK. Two of these cases healed within 7 days, the other case required 18 days to heal. Sixty-three per cent of persistent corneal erosions treated with debridement healed after one procedure; however, only four out of 19 cases (21%) were healed at the first revisit. Complications were rare: corneal edema occurred in two cases following multiple GK, and excessive granulation tissue in one case was managed with a SK. There was the occurrence of an ulcer adjacent to the surgery site in four cases, two cases following GK and two cases following SK.

Women 70 years of age or older who were enrolled in these trials were similar to their younger counterparts in response rates, time to disease progression, survival, and toxic effects. Women in this age group should not be excluded, based on age alone, from clinical trials involving chemotherapy for advanced breast cancer.

Picture a group of three elementary music teachers and a university professor who meet weekly to eat, talk about music teaching practice, share stories from the week, and laugh. The group is close-knit; they enjoy getting together on Thursday afternoons to watch video from the teachers' classrooms. The teachers gather weekly because they have committed to making their classrooms places where students learn through collaborative, active music-making. They want to figure out ways to help their students to infuse class projects with creativity and energy. These teachers don't want to create an artificial or manufactured music environment for their students, with worksheets, or karaoke-style soundtracks. Instead, they want their students to watch, listen to, and respond to one another like musicians in a jazz quintet or symphony orchestra. All of them share a belief in Bruner's (1960) assertion that "any subject can be taught effectively in some intellectually honest form to any child at any stage of development" (p. 33). They want even their youngest students to learn musical skills and make real music, not just read about it or do make-believe, watered-down musical activities. None of the teachers has all the answers. In fact, all of them have struggled to incorporate their ideals within the real-world strictures of public school music. What they

A computer program—FACTUS (fracture analysis of crack tips using SPATE)—has been developed for the efficient analysis of thermoelastic data obtained from around a crack tip. The program is based on earlier work for the determination of stress intensity factors (SIFs), and also includes a novel solution procedure for the derivation of the non‐singular stress term σ0x . The program has been used in the analysis of a series of large plate specimens with central or edge slots/cracks. The derived SIFs are compared with independent values. Issues, e.g. crack closure and the extent and effect of the plastic zone, are discussed.