To present a patient with polypoidal choroidal vasculopathy, an entity often overlooked and misdiagnosed in daily clinical practice.A 73-year-old patient with reduced visual acuity in the left eye was evaluated with a complete ophthalmological examination, fundus photography, optical coherence tomography of the posterior segment of the eye, and optical coherence tomography with angiography and a diagnosis of polypoidal choroidal vasculopathy with development of a type 1 choroidal neovascular network (aneurysmalpolypoidal network) was made.The changes shown on OCT referred to the presence of subretinal fluid, PED in the shape of the letter M, the presence of a "double layer sign" from the developed neovascular network in the form of a renal glomerulus. After application of an anti-VEGF preparation (Aflibercept) for a period of six months (five applied doses, three consecutive, and two every two months) there was regression of the lesion and improvement of visual acuity from 0.5 to 0.9 according to the Snellen optotype.The characteristic changes of OCT and OCT-A, as well as the course of the disease corresponded with the literature data that we consulted during the evaluation of this case, thus the diagnosis of polypoidal choroidal vasculopathy was confirmed. Timely recognition of this not so rare entity is of great importance for appropriate management and treatment of the affected patient.

Ocular surface squamous neoplasia (OSSN) is a clinical term that includes epithelial dysplasia of various degrees, carcinoma in situ to invasive squamous cell carcinoma of the conjunctiva. Several procedures are used today to diagnose these lesions: biopsy with pathohistological analysis, cytology, in vivo confocal microscopy, ultrasound biomicroscopy, AS-OCT (Optical Coherence Tomography of the Anterior Segment) and OCT-A (Optical Coherence Tomography-Angiography).Aim: To present the possible diagnostic and therapeutic modalities that are used today in dealing with OSSN, as well as to optimize the management of these lesions in everyday clinical practice, in order for the patient to receive appropriate treatment.Case report, methods and results: In this paper we present the case of a 71-year-old patient, presented for an ophthalmological examination last year at the Clinic for Eye Diseases in Skopje. The patient reported a foreign body sensation and irritation of the right eye due to a tumor formation in the temporal limb that was gradually increasing over the past two years. Biomicroscopic examination and AS-OCT established a clinical diagnosis of OSSN. The lesion was excised and sent to the Institute of Pathology in Skopje, pathohistologically confirmed for in situ carcinoma of the conjunctiva.Conclusion: AS-OCT, surgical excision, and pathohistological examination are the "optimal triad" in the management of these lesions.

Presentation of a patient with a squamous cell carcinoma of the conjunctiva on his left eye A 83-year -old man with a squamous cell carcinoma of the conjunctiva was examined and treated at the University Eye Clinic in Skopje, by the ophthalmologist, after an ophthalmological examination and observation in the small countryside-ophthalmology department for a year.Near the temporal limbus at 3 o'clock there was present nodous and white tumorous lesion around 1,4 cm. weath with elevation from the eye surface of 0,5 cm. Around the tumor there was local vascularization. External photographs were taken to document the lesion.The excision biopsy was performed. Topical antibiotic-steroid combination of eye drops was applied 3 times daily for 4 weeks after the primary excision of tumor.The diagnosis was pathohistologically confirmed at the Institute of Pathology in Skopje. Primary excision biopsy is preferably therapy and treatment. Also the primary excision biopsy is a golden standard for proper diagnosis for small squamous cell carcinoma of conjunctiva.