Background The two most commonly used modalities of teledermatology (TD) are store-and-forward (SF) and live-interactive (LI) TD. Existing studies have not compared these tools with respect to patient and provider satisfaction. Objective To systematically review all published studies of patient and provider satisfaction with SF and LI TD. Methods PubMed, EMBASE, and Cochrane databases were systematically searched for studies on provider or patient satisfaction with SF or LI TD between January 2000 and June 2016. Results Forty eligible studies were identified: 32 with SF TD, 10 with LI TD, and 2 evaluating both. With SF TD, 96% of studies assessing patient satisfaction and 82% of studies assessing provider satisfaction demonstrated satisfaction ( n = 24 and 17, respectively). With LI TD, 89% of studies assessing patient satisfaction and all studies assessing provider satisfaction revealed satisfaction (n = 9 and 6, respectively). Conclusion Patients and providers are satisfied with both SF and LI TD. Studies assessing satisfaction with LI have not been conducted in recent years, and have only been conducted in limited geographic patient populations. Further research assessing satisfaction with TD will help address any dissatisfaction with its uses and allow for increased support and funding of future programmes.
Prevalence of squamous cell carcinoma in patients with chronic hidradenitis suppurativa A review of the articles found 85 cases of SCC arising from HS reported in the English literature to date (6-13). A 2016 report by Jourabchi et al. (6) described 80 of these cases, and we found five additional cases published since that time (Table 2). Among these five new cases, the mean history of HS prior to SCC diagnosis was 26 years. The mean age at diagnosis was 52 years. SCC developed from longstanding HS of predominately the gluteal and perianal areas. A biopsy of malignant tissue was tested for human papillomavirus (HPV) in two of the five cases, and was negative in both cases. A history of tobacco use was reported in two cases (9, 10). The diagnosis of SCC in chronic HS is particularly challenging because painful and inflammatory HS lesions may be difficult to distinguish from malignant transformation (6). Thus, a low threshold for biopsy is often recommended by clinicians to diagnose
Background
Finite clinical data and understanding of COVID-19 immunopathology has led to limited, opinion-based recommendations for management of immune-mediated inflammatory disease (IMID) patients on immunosuppressive (IS) therapeutics.
Objective
Determine if IS therapeutic type impacts COVID-19 risk among IMID patients.
Methods
We conducted a retrospective cohort analysis of Henry Ford Health System (HFHS) patients tested for COVID-19 between February 1
st
and April 18
th
, 2020 treated with IS medication for IMID. Therapeutic class of IS medication, comorbidities, and demographic factors were combined into multivariate models to determine predictors of COVID-19 infection, admission, ventilation, and mortality.
Results
Of 213 IMID patients, 36.2% tested positive for COVID-19, who had no greater odds of being hospitalized or requiring ventilation relative to the general population. No IS therapeutic worsened the course of disease after multivariate correction, though multi-drug regimens and biologics predicted an increased and decreased rate of hospitalization, respectively, with the latter driven by TNFα inhibitors.
Limitations
A single-center study somewhat limits generalization to community-based settings. Only patients tested for COVID-19 were analyzed.
Conclusion
IS therapies for IMIDs are not associated with a significantly greater risk of SARS-CoV-2 or severe sequelae when controlling for other factors, and TNFα inhibitors may decrease odds of severe infection.
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