Practice Points• In studies that implemented strength training and measured gait outcomes, this review found a trend for significant improvement in strength outcomes, however not for gait performance as measured by speed and endurance.• This review found that studies including strength training for people with MS, either alone or in combination with other rehabilitation interventions, are typically prescribed in a manner consistent with current guidelines, and can improve strength. However, in order to improve gait, future studies might consider exploring higher intensities or frequencies.• This review found that strength training exercises most often focused on the knee and were performed on weight machines in a sitting position. This may be a reason strength training has not resulted in consistent improvements in gait, and future studies are needed that investigate muscle targets, positions, and modes of exercise that are functionally relevant to gait. www.ijmsc.org International Journal of MS Care PreprintO n l i n e F i r s t 3 Abstract Background: There are mixed reports on the effectiveness of strength training to improve gait

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