Time-resolved MR angiography allows determination of cardiopulmonary transit times that are significantly prolonged in heart failure and correlate directly with LV volumes and inversely with LV ejection fraction.
LV mass was determined most accurately by using manual contours on true FISP images. In these animal models, fully automatic segmentation of true FISP images was performed in one-sixth of the time of manual segmentation and yielded LV masses with a mean error of approximately 5% of true LV mass.
Transit times measured with MR imaging may help in discrimination between patients with and patients without heart disease, independently of other cardiac functional parameters.
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