Optical coherence tomography (OCT) has revolutionised clinical ophthalmology. The translation of OCT into the operating room is a natural next step given its high-resolution anatomic information. Contrast agents and enhancement have significantly improved the diagnostic capabilities of numerous imaging modalities (such as CT and MRI). The use of OCT contrast agents in ophthalmology has been generally lacking. In this report, we describe the novel application of triamcinolone as an OCT contrast agent for intraoperative OCT to improve visibility of tissue interfaces and planes (eg, posterior hyaloid insertion points). The application of this technology may have wide-ranging implications for enhanced image-guided surgery, intraoperative OCT and dynamic or functional applications of OCT technology.

There was no significant difference in any corresponding MPLD or temporal/nasal MPLD ratio between the postoperative eyelid and the postoperative control eyelid. This technique for CM ± T blepharoptosis repair adequately restores eyelid contour.

Summary Optical coherence tomography (OCT) based visualization of ophthalmic anatomy has transformed the clinical practice of ophthalmology. The translation of OCT into the surgical theater is currently being actively researched and may provide a paradigm shift in surgical practice. Enhanced visualization of tissues and tissue planes may provide further iterative improvement in surgeon feedback. Contrast enhanced intraoperative OCT (iOCT) has been previously described with triamcinolone. In this report, we describe the OCT features and contrast enhancement noted with indocyanine green utilizing iOCT in human subjects as well as an ex vivo analysis in porcine eyes.