The reaction of uranyl nitrate with 1,3-bis(salicylideneamino)-2-propanol (H(3)L1) and 1,3-bis(3,5-di-tert-butylsalicylideneamino)-2-propanol (H(3)L2) in the presence of triethylamine (Et(3)N) yielded hydroxy- and alkoxy-bridged dinuclear complexes; [(UO(2))(2)(L1)(OH)(MeOH)(2)].(MeOH)(2) (.(MeOH)(2)) and [(UO(2))(2)(L2)(OH)(MeOH)(2)].(MeOH)(2) (.(MeOH)(2)). The crystal structures of .(DMF)(2) and .(DMF)(2) exhibit an unsymmetrical central U(2)O(2) core involving bridging alkoxy- and hydroxy-oxygen atoms. The geometry around the uranium center in .(DMF)(2) and .(DMF)(2) is that of a distorted pentagonal bipyramid with the solvent molecule occupying the fifth coordination site. The flexible nature of the ligand backbone is more pronounced in .(DMF)(2) compared to .(DMF)(2), yielding two molecules per unit cell in different conformations. Under similar reaction conditions, using ethylenediamine as a base, the respective Salen-based uranyl compounds, [UO(2)(Salen)(MeOH)] () and [UO(2)(Bu(t)(2)-Salen)(MeOH)] () are obtained due to transamination of the ligand backbone. Complexes .(MeOH)(2) and .(MeOH)(2) when reacted with an excess of ethylenediamine failed to yield the respective Salen-based complexes, and , respectively. The new compounds have been characterized using solution (NMR and UV-Vis) and solid-state (IR, X-ray crystallography) techniques. Hydrolysis of .(MeOH)(2) and .(MeOH)(2) in the pH range 1-14 was studied using UV-Vis spectroscopy and compared with the hydrolysis of and [UO(2)(Salophen)(MeOH)] (). A two-phase extraction study suggests quantitative removal of uranyl ions from the aqueous phase at higher pH conditions.

Uranyl Schiff base complex [(UO(2))(2)(Salpro)(OH)(Solvent)(2)] (1) in the presence of excess of ethylenediamine (EDA) does not undergo nucleophilic addition (hydrolysis) and substitution (transamination) reactions due to an extended chelation [2N, 3O + OH] by the flexible backbone.

Endovascular intervention has become the mainstay for treatment of most patients suffering from peripheral vascular disease. We describe a patient with a known nickel allergy who underwent placement of a stainless steel stent for aortoiliac occlusive disease. Despite our attempt to avoid a nickel-containing stent, the patient developed a diffuse rash consistent with a nickel or metal allergy. A review of stainless steel metallurgy revealed that nickel, cobalt, and titanium are frequently used to provide anticorrosive properties to stainless steel. The clinical significance of the use of nickel-alloy stents in the setting of patients with a nickel allergy is discussed.

Purpose To explore the relationship between degree of rurality and glucose (hemoglobin A1c), blood pressure (BP), and lipid (LDL) control among patients with diabetes. Methods Descriptive study; 1,649 patients in 205 rural practices in the United States. Patients’ residence ZIP codes defined degree of rurality (Rural-Urban Commuting Areas codes). Outcomes were measures of acceptable control (A1c <= 9%, BP < 140/90 mmHg, LDL < 130 mg/dL) and optimal control (A1c < 7%, BP < 130/80 mmHg, LDL < 100 mg/dL). Statistical significance was set at P < .008 (Bonferroni’s correction). Findings Although the proportion of patients with reasonable A1c control worsened by increasing degree of rurality, the differences were not statistically significant (urban 90%, large rural 88%, small rural 85%, isolated rural 83%; P = .10); mean A1c values also increased by degree of rurality, although not statistically significant (urban 7.2 [SD 1.6], large rural 7.3 [SD 1.7], small rural 7.5 [SD1.8], isolated rural 7.5 [SD1.9]; P = .16). We observed no differences between degree of rural and reasonable BP or LDL control (P = .42, P = .23, respectively) or optimal A1c or BP control (P = .52, P = .65, respectively). Optimal and mean LDL values worsened as rurality increased (P = .08, P = .029, respectively). Conclusion In patients with diabetes who seek care in the rural Southern US, we observed no relationship between degree of rurality of patients’ residence and traditional measures of quality of care. Further examination of the trends and explanatory factors for relative worsening of metabolic control by increasing degree of rurality is warranted.

Applied chemistry Z 0300 Actinide Selective Systems for Environmental Extraction and Sensing Applications -[16 refs.]. -(WU, X.; BHARARA, M. S.; TATE, B. K.; TONKS, S. A.; VILSECK, J. Z.; GORDEN, A. E. V.; Mater. Res. Soc. Symp. Proc. 1104 (2008); Dep. Chem. Biochem., Auburn Univ., Auburn, AL 36849, USA; Eng.) -Lindner 25-275