Numerous conditions affect the occipitocervical junction requiring treatment with occipitocervical fixation. In this paper the authors present their technique of craniocervical fixation achieved with the cephalad extension of posterior C1-3 polyaxial screw and rods to polyaxial screws placed in the occipital condyles. They retrospectively analyzed occipital condyle morphology obtained from CT analyses of 40 patients with normal cervical spines, evaluated occipital condyle screw placement feasibility in 4 cadavers, and provided a case report of a 70-year-old woman with rheumatoid arthritis, basilar invagination, and atlantoaxial instability who was treated with this novel technique. Based on radiographic analysis of occipital condyle anatomy, they concluded that on average a 3.5-mm-diameter x 20- to 30-mm-long screw can be safely placed at an angle of 20-33 degrees from the sagittal plane. Overall, measuring the condylar heights (mean [+/- SD] 10.8 +/- 1.5 mm, range 8.1-15.0 mm), widths (mean 11.1 +/- 1.4 mm, range 8.5-14.2 mm), lengths (20.3 +/- 2.1 mm, range 15.4-24.6 mm), and angles (mean 32.8 +/- 5.2 degrees , range 20.2-45.8 degrees) by using CT studies is an accurate and precise method. This finding correlates with the results of prior anatomical studies of occipital condyles and is important in the planning of craniovertebral junction surgery.
IntroductionDural sinus venous thrombosis is a rare but potentially devastating disease. Current therapies include intravenous heparin, direct mechanical thrombectomy and local chemical thrombolysis. Despite aggressive management of this disease with these therapeutic interventions there are treatment failures that may be amenable to endovascular intervention. To date there is no endovascular device made specifically for this purpose.MethodsThree patients presented with neurological symptoms related to increased intracranial pressure. Non-invasive imaging demonstrated cerebral sinus occlusion. All patients were initially treated with intravenous heparin. The first patient had bilateral transverse and sigmoid sinus and superior sagittal sinus thrombosis, the second had left transverse and sigmoid sinus thrombosis and the third patient had thrombosis of the left transverse sinus which extended into the sigmoid sinus and internal jugular vein. All patients were neurologically deteriorating at the time of intervention and had developed hemorrhagic strokes despite aggressive heparinization.ResultsAll of the patients were successfully revascularized angiographically with the Penumbra Aspiration System in combination with local chemical thrombolysis. The first patient had end stage renal disease and significant comorbidities and eventually succumbed to multiorgan failure secondary to her pre-existing disease. The second patient developed leg weakness prior to the thrombolysis which progressed to paraplegia post-thrombectomy. Her leg strength was improving at discharge (4/5) and she was able to ambulate with assistive devices. She lives at home 2 months post-thrombectomy and ambulates without assistance. The third patient required hemicraniectomy for left parietal hemorrhage. She was discharged to rehab and returned for follow-up at 6 months with minimal word finding difficulties and otherwise neurologically intact. Both survivors were converted to warfarin therapy on discharge.ConclusionSuccessful revascularization was achieved in all three patients using a combination of thrombectomy with the Penumbra Aspiration System and local thrombolysis. All patients were severely injured secondary to sinus thrombosis related strokes; however, aggressive escalation of therapy along with successful revascularization resulted in very good long term outcomes in two patients. To our knowledge these are the first of such cases reported to use the Penumbra Mechanical thrombectomy device to re-canalize the dural venous sinus system.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.