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Background: The COVID-19 pandemic has had a significant impact on societies all over the world, leading to significant shifts in individual behavior as well as societal norms. The goal of this study was to provide an in-depth look at the many different aspects of public behavior during the COVID-19 pandemic. Methods: Demographic information, COVID-19 knowledge and awareness, prevention adherence, vaccination attitudes, and psychological well-being as a whole were all be gathered through the quantitative survey. The subjective meetings will give further bits of knowledge into the hidden inspirations, discernments, and difficulties faced by people in following general wellbeing rules. Results: To find patterns and correlations among the various variables, statistical methods like regression analysis, factor analysis, and clustering algorithms were used in the data analysis. The subjective information was investigated specifically, separating key topics and accounts that shed light on the subtleties of the public’s way of behaving during the pandemic. Conclusions: In the end, the goal of this multidimensional study was to help make decisions based on evidence and come up with plans to improve public health and lessen the impact of infectious disease outbreaks like COVID-19.

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Juvenile idiopathic arthritis (JIA) is one of the most common and most disabling rheumatic diseases in children. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with unknown etiology, which is based on a genetically determined dysregulation of immunity. In recent years, the view of JIA and SLE as potentially incurable and prognostically unfavorable diseases has been revised. This is largely due to the expansion of the possibilities of early diagnosis of JIA, SLE, which allows starting active therapy at the onset of the disease, the development of a new class of basic anti-inflammatory drugs, and scientific research in the genetics of both diseases. A large number of genes associated with immune responses can, induce an autoimmune response - the leading pathogenetic link in both diseases. The article presents modern data on the possible pathogenesis, spectrum of clinical manifestations of juvenile idiopathic arthritis (JIA) and systemic lupus erythematosus (SLE) in children. A brief description of the pathological changes in JIA and SLE is given. Possible factors are considered, incl. genetic, affecting the predisposition to the disease, the process of the formation of organ damage. The issues of assessing the activity of diseases, assessing the quality of life of patients are discussed in detail.