We present a new measurement of the positive muon magnetic anomaly, a µ ≡ (gµ − 2)/2, from the Fermilab Muon g −2 Experiment based on data collected in 2019 and 2020. We have analyzed more than four times the number of positrons from muon decay than in our previous result from 2018 data. The systematic error is reduced by more than a factor of two due to better running conditions, a more stable beam, and improved knowledge of the magnetic field weighted by the muon distribution, ω′ p , and of the anomalous precession frequency corrected for beam dynamics effects, ωa. From the ratio ωa/ω ′ p , together with precisely determined external parameters, we determine a µ = 116 592 057(25) × 10 −11 (0.21 ppm). Combining this result with our previous result from the 2018 data, we obtain a µ (FNAL) = 116 592 055(24) × 10 −11 (0.20 ppm). The new experimental world average is aµ(Exp) = 116 592 059(22) × 10 −11 (0.19 ppm), which represents a factor of two improvement in precision.
A risk prediction model is a mathematical equation that uses patient risk factor data to estimate the probability of a patient experiencing a healthcare outcome. Risk prediction models are widely studied in the cardiothoracic surgical literature with most developed using logistic regression. For a risk prediction model to be useful, it must have adequate discrimination, calibration, face validity and clinical usefulness. A basic understanding of the advantages and potential limitations of risk prediction models is vital before applying them in clinical practice. This article provides a brief overview for the clinician on the various issues to be considered when developing or validating a risk prediction model. An example of how to develop a simple model is also included.
Patient risk factors and case-mix in adult cardiac surgery change dynamically over time. Models like the EuroSCORE that are developed using a 'snapshot' of data in time do not account for this and can subsequently lose calibration. It is therefore important to regularly revalidate clinical prediction models.
Clinical registries will have an increasingly important role to play in health-care, with a number already established in cardiac surgery. This review covers the fundamentals of establishing and managing clinical registries, including legal and ethical frameworks along with intellectual property attribution. Also discussed are important issues relating to the processing of data, data extraction and conducting analyses using registry data.
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