Aim: To study the histomorphological pattern of disease in endobronchial biopsy in Nepalgunj Medical College Teaching Hospital (NGMCTH), Kohalpur. Background: Study of endobronchial biopsy is mainly indicated for malignancies, however, various other conditions including inflammatory pathology can be correctly identified. Material and Methods: This is a hospital based descriptive study carried out at Department of Pathology, NGMC, Kohalpur from August 2017 to July 2018. The study included 51 cases of endobronchial biopsy. All bronchial biopsies were processed according to the standard method and the detail microscopic findings were studied and the data were analysed statistically. Result: The age of patients ranged from 20-80 years. Cough was the most common presenting symptom. Most common benign pathology was tuberculosis and among malignancies squamous cell carcinoma was common histopathological diagnosis. Conclusion: Identification of lung pathology at early stage with correct histological morphology is important to decrease morbidity and mortality related to both benign and malignant condition.

Introduction: Bronchoalveolar lavage has a high diagnostic utility for cytology and bacteriology. It can be done as an outpatient procedure for both immunocompetent and immunocompromised patient. Material obtained by bronchoalveolar lavage can give a definite diagnosis in conditions such as infections and malignancies. Aim: The aim of this study was to assess the diagnostic value of bronchoalveolar lavage (BAL) in cases which underwent routine bronchoscopy for evaluation of lung disease. Materials and methods This is a hospital based descriptive study done from 16th  June 2016 to 15th  June 2017. One hundred twenty bronchoalveolar lavage (BAL) cases were analyzed for differential count, cytological evaluation and bacteriological examination. All cases were included which were sent as BAL specimen to the laboratory department. Bronchoscopy was done as an outpatient procedure and lavage fluid obtained was analyzed. Result: Out of 120 cases, 69 were male and 51 were female. The age ranged from 10 to 80 years. Among 120 cases, eight (n= 6.66%) cases were unsatisfactory, twelve (n= 10%) cases were of tuberculosis, one (n= 0.83%) case was of fungal infection, two (n= 1.67%) cases were of malignancy, ninety one (n= 75.84%) cases were of small airway infection and six cases were satisfactory but with no diagnostic value. (n= 5%). Conclusion Bronchoalveolar lavage is valuable in diagnosis of tuberculosis, infections and malignancies.