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Multimodal learning, as an effective method to helping students understand complex concepts, has attracted much research interest recently. Our motivation of this work is very intuitive: we want to evaluate student performance of multimodal learning over the Internet. We are developing a system for student performance evaluation which can automatically collect student-generated multimedia data during online multimodal learning and analyze student performance. As our initial step, we propose to make use of a vector space model to process student-generated multimodal data, aiming at evaluating student performance by exploring all annotation information. In particular, the area of a study material is represented as a 2-dimensional grid and pre-defined attributes form an attribute space. Then, annotations generated by students are mapped to a 3-dimensional indicator matrix, 2-dimensions corresponding to object positions in the grid of the study material and a third dimension recording attributes of objects. Then, recall, precision and Jaccard index are used as metrics to evaluate student performance, given the teacher's analysis as the ground truth. We applied our scheme to real datasets generated by students and teachers in two schools. The results are encouraging and confirm the effectiveness of the proposed approach to student performance evaluation in multimodal learning.

<p>Supplementary Table 1 and Supplmentary Figures 1-3 Legends</p>

<p>CELSR3 is a target for T-cell redirection therapeutics. <b>A,</b> CELSR3xCD3 bs-mAb directs T-cell mediated cytotoxicity in CELSR3(+) TCCSUP NLR and PM154 NLR but not CELSR3(−) DU145 NLR, TCCSUP CELSR3 KO cell lines. 5:1 (exp. 1) or 10:1 (exp. 2) pan T cells to tumor cells were added to each well along with CELSR3xCD3 bs-mAb and imaged using the IncuCyte S3 platform. Maximum cell lysis occurred by day 7 timepoint. At least three biological replicates were analyzed from one independent experiment. <b>B,</b> Cell surface expression of CELSR3 on tumor cell lines determined by quantitative flow cytometry and calculated from at least 10,000 events per sample. Dotted line denotes assay lower limit of detection.</p>