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New Synthesis of Donepezil Through Palladium-Catalyzed Hydrogenation Approach. -A new and efficient process is presented for the large-scale synthesis of donepezil (IV), an anti-Alzheimer drug. The process involves the catalytic hydrogenation of (I) as the key step. -(ELATI, C. R.; KOLLA, N.; CHALAMALA, S. R.; VANKAWALA, P. J.; SUNDARAM, V.; VURIMIDI, H.; MATHAD*, V. T.; Synth. Commun. 36 (2006) 1-3, 169-174; Dep. Res. Dev., Dr. Reddy's Lab. Ltd., Bollaram, Jinnaram 502 325, India; Eng.) -M. Bohle 22-147