Editorial on the Research Topic Oxidative stress related to cellular metabolism in lung health and diseasesCellular metabolism is constantly exposed to oxidants that are produced either endogenously (e.g., by mitochondrial electron transport during respiration or the activation of phagocytes) or exogenously (e.g., by air pollutants and cigarette smoke) (Wilson et al., 2002; Sharifi-Rad et al., 2020). ROS-mediated damage to the lungs is facilitated by the high oxygen concentration in the lungs as well as their large surface area and blood supply. Due to an imbalance of oxidants/antioxidants favoring oxidants, oxidative stress causes the oxidation of proteins, DNA, and lipids, and causes secondary metabolic ROS production in cells (Sies, 1991;Park et al., 2009). The role of oxidative stress in lung diseases such as asthma, bronchial asthma (BA), chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), acute lung injury, and pulmonary fibrosis has now been established (Park et al., 2009).According to Adeloye et al. (2022), COPD was the third leading cause of death among people aged 30-79 in 2019, affecting approximately 391.9 million people worldwide. In 2015, 0.4 million people died from asthma, making it the most prevalent chronic childhood medical condition (
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.