Background: In Indonesia, around 400 health workers died due to Covid-19 between June-July 2021, therefore the health workers need to be given further immunity. Health workers were among the first to get a booster shoot. However, they may experience side effects after vaccination. We aimed to describe side effects of Moderna vaccine as a booster in health workers. Methods: A cross sectional study was conducted on health workers who received mRNA Covid-19 vaccine booster (Moderna) at Sulianti Saroso Infectious Disease Hospital, Indonesia and had filled the questionnaire assessing side effects form. We associated the form of the questionnaire assessing side effects from the originating source of hospital immunization unit in September 2021. Results: A total of 101 health workers who received mRNA Covid-19 vaccine booster in Jul-Aug 2021 were included. Most of health worker experienced more than 3 side effects. The side effects were sore arm (100%); chills (72%); fatigue (57%); headache (53%) and fever (51%), other symptoms (28%). The side effects mostly happened a day of receiving a booster shot (61.4%). There was no association between age, gender, comorbid to amount of side effects (P>0.05). Conclusion: Since the public must fulfil the immunization program during pandemic, it is the responsibility of the healthcare provider to inform about the potential side effects and benefits of a new Covid-19 vaccine.

<em>This research was conducted to determine the effect of the factors driving MSEs in making loans to peer-to-peer lending companies. Factors that are considered by MSEs in seeking financial resources through peer-to-peer lending are loan processes, interest rates, loan processing costs, loan amounts, and loan application flexibility. These five factors will then be used as independent variables to see behavioral intentions and the actual use of a peer-to-peer lending platform. <em>This research method uses Structural Equation Modeling (SEM) and WrapPLS 6.0 test equipment. <em>The results of this study found that the loan process had no significant effect on behavioral intentions and other factors had a positive influence and the highest factor affected MSEs borrowing on this platform was the flexibility of loan applications. With the aspirations of MSEs, peer-to-peer lending companies in Indonesia can improve services so that business capital loan transactions increase and advance the economy of MSEs in Indonesia.</em></em></em>

Uncoupling Protein 2 (UCP2) dan Uncoupling Protein 3 (UCP3) is a mitochondrial transmembrane carriers which uncouple the transport of protons across the inner mitochondrial membrane from electron transport and the synthesis of ATP from ADP. The UCPs play a role in energy homeostasis and have considered to be candidate gene for controlling obesity and insulin resistance. The aim of our study is to analyze UCP2 and UCP3 polymorphisms as risk factors of insulin resistance in obese adoslescent.A case control study was conducted in Junior High School in Semarang, Central Java, Indonesia during [2007][2008]. Seventy five subjects included in this study. Height, weight and body mass index (BMI) were measured. Insulin resistance was estimated by using the homeostasis model assessment (HOMA-IR) score which calculated as fasting insulin (microU/mL) x fasting glucose (mmol/L)/22.5. Three polymorphic sites i.e. UCP3 -55c/t, UCP3 Y210Y, and UCP2 A55V were investigated by using the Restriction Length Fragment Polymorphism. The data were analyzed by 2x2 table and odd rasio with 95% confidence interval.There were 38 obese (27 male, 11 female) and 37 normoweight ( 25 male, 12 female) subject with the mean age was 13.2 (SD 0.32) years. Of 38 obese, there were 3 (7.9%) subject had insulin resistance. None of normoweight subjects had insulin resistance. There was a significant correlation between BMI and insulin resistance (r = 0. 601, p< 0.001). Of 38 obese subject, C allele of UCP2 A55V and C allele of UCP3 Y210Y are a risk factors of insulin resistance (OR 2.45, 95% CI 1.97-3.04 , p< 0.0001 ; OR 2.6, 95% CI 2.10-3.24, p< 0.0001 respectively), whereas UCP3 -55c/t was not considered as risk factors of insulin resistance.Our study suggest that C allele of UCP2 A55V and C allele in UCP3 Y210Y are a risk factors of insulin resistance in Indonesian obese adolescent. Larger studies is needed to prove the role of UCPs in controlling insulin resistance.

Background Obesity in children is becoming a global epidemic.Non􀀷alcoholic fatty liver disease (NAFLD) is a highly prevalentand potentially serious complication of childhood obesity. Theearly identification of fibrosis is important in children v.ith NAFLDin order to prevent the development of liver disease in adulthood.One non􀀷invasive procedure to predict liver fibrosis is the aspartateaminotransferase (AST)􀀷platelet ratio index (APRI).Objective The purpose of our study was to assess a correlationbetween APRI and body mass index (BMI) in obese childrenwith fatty liver.Methods A cross􀀷sectional study was conducted from August toSeptember 2007. Subjects were obese children from one juniorhigh school in Semarang. Complete blood count, transaminaseenzyme measurement, and abdominal ultrasound (USG) wereperformed on each subject. Only subjects with bright liver onUSG underwent APRI analysis. Spearman's correlation was usedfor statistical analysis.Results Of 3 7 obese children, 19 children had bright liver on USG.Their mean APRI was 0.16 (SD 0.119). Only one obese subject(1137) with bright liver had an APRI > 0.5. APRI was significantlycorrelated to alanine amino transferase (ALT) levels (r = 0.62),but not significantly correlated to weight and BMI.Conclusion There was no correlation between APRI and BMI.Only lout of 37 obese children with fatty liver had APRI levelsindicating the presence of liver fibrosis. [Paediatr Indones.2012;52:181-4].