AIMTo compare efficacy of MDI (Metered dose inhaler) with spacer and without spacer using combination drugs of fluticasone and salmeterol in childhood bronchial asthma. MATERIALS AND METHODSA prospective study was planned with 56 patients of both sexes in the age group of 5-12 years, who reported to Asthma Clinic and fulfilled inclusion and exclusion criteria after parental consent. All patients included in the trail were initially entered into runin period of 2 weeks, during which a record was maintained of their clinical parameters and allowed to take their prescribed medication. At the end of run-in period the baseline symptoms and signs of asthma, PFT, amount of rescue medication and nocturnal awakening due to asthma symptoms were recorded. After run-in period, based on computer generated random number tables, patients were randomized to receive MDI (Fluticasone 125 micrograms and salmeterol 25 micrograms) either with spacer or without spacer. Statistical analysis was performed to compare both groups. CONCLUSIONThe present study demonstrated that there is no significant difference between with spacer group and without spacer group in clinical and PFT improvements in childhood bronchial asthma.

AIM:To evaluate efficacy of Rotahaler with fluticasone and salmeterol medication in childhood bronchial asthma. MATERIALS AND METHODS: A prospective study was planned with 30 patients of both sexes in the age group of 5-12 years, who reported to asthma clinic and fulfilled inclusion and exclusion criteria were included in the study after parental consent. All patients included in the trail were initially entered in to run-in period of 2 weeks, during which a record was maintained of their clinical parameters and allowed to take their prescribed medication. At the end of run-in period the base line symptoms and signs of asthma, PFT, amount of rescue medication and nocturnal awakening due to asthma symptoms were recorded and Rotahaler with test medication applied. Statistical analysis was performed on pre and post intervention data. CONCLUSION:The present study demonstrated that Rotahaler a dry power devise is significantly effective in producing clinical and PFT improvement, in moderate persistent asthma in children.

AIMTo compare efficacy of Rotahaler and Accuhaler using combination drugs of fluticasone and salmeterol in childhood bronchial asthma. MATERIALS AND METHODSA prospective study was planned with 60 patients of both sexes in the age group of 5-12 years, who reported to Asthma Clinic and fulfilled inclusion and exclusion criteria after parental consent. All patients included in the trial were initially entered into runin period of 2 weeks, during which a record was maintained of their clinical parameters and allowed to take their prescribed medication. At the end of run-in period the baseline symptoms and signs of asthma, PFT, amount of rescue medication and nocturnal awakening due to asthma symptoms were recorded. After run-in period, based on computer generated random numbered tables patients were randomized to receive either Rotahaler or Accuhaler with same combination medication. Statistical analysis was performed to compare both groups. CONCLUSIONThe present study demonstrated that there is no significant difference between Rotahaler and Accuhaler in clinical and PFT improvements in childhood bronchial asthma.

AIMTo evaluate efficacy of Accuhaler with fluticasone and salmeterol medication in childhood bronchial asthma. MATERIALS AND METHODSA prospective study was planned with 52 patients of both sexes in the age group of 5-12 years, who reported to Asthma Clinic and fulfilled inclusion and exclusion criteria after parental consent. All patients included in the trial were initially entered into a run-in period of 2 weeks, during which a record was maintained of their clinical parameters and allowed to take their prescribed medication. At the end of run-in period the baseline symptoms and signs of asthma, PFT, amount of rescue medication and nocturnal awakening due to asthma symptoms were recorded and Accuhaler with test medication applied. Statistical analysis was performed on pre-and post-intervention data. CONCLUSIONThe present study demonstrated that Accuhaler, a dry power device, is significantly effective in producing clinical and PFT improvement in moderate persistent asthma of children.