No abstract

Objective: This research work focus on synthesis of silver nanoparticles from Morinda tinctoria Roxb leaves. The synthesis of nanoparticles from biological processes is evolving a new era of research interests in nanotechnology. Silver nanoparticles are usually synthesized by chemicals. M. tinctoria Roxb leaves are reputed plant in traditional system of medicine and it is used for the treatment of illness such as arthritis, cancer, gastric ulcer and other heart disease etc. Methods:The present study the leaves were collected, air dried and subjected to synthesis of silver nanoparticles (MtNps). The obtained nanoparticles from M. tinctoria Roxb leaves was characterized and antimicrobial activity, antidiabetic and anticancer activity was analyzed by standard procedures.Results: M. tinctoria silver nanoparticles study showed the evaluation of antioxidant and anticancer activity. Antioxidant activities were done using DPPH antioxidant assay and hydrogen peroxide assay. The anticancer study was conducted to evaluate the in-vitro anticancer activity of green synthesized nanoparticles using human hepatic carcinoma cell lines (HepG2).Conclusions: M. tinctoria silver nanoparticles evaluation showed higher antioxidant activity and anticancer activity in M. tinctoria Roxb.

Dengue disease is a mosquito vector borne viral disease which is transmitted mostly by the Aedes aegypti mosquito vector species. Other viral diseases such as chikungunya, yellow fever and zika are also caused by this vector. After feeding on a DENV-infected person, the virus replicates in the mosquito midgut then it distributes to other tissues. Medicinal plant species contains wide series of phytochemicals such as primary and secondary metabolites that produce biological activities and defenses against mosquitoes. In the current study, a methanol leaf extract of Aegle marmelos was assessed for larvicidal efficacy and midgut alteration of third instar Ae. aegypti larvae. After the larvicidal bioassay, the probit analysis identified Lc50 in this extract that killed the larvae at the concentration of 49 ppm. Proteomic analysis and in-silico studies revealed that the predicted protein could disrupt the larvae midgut because of the Aegle marmelos natural bioactive compounds and secondary metabolites. Our approach is to identify the inhibitor proteins that bound to midgut of Ae. aegypti larvae after treatment with the Aegle marmelos bioactive compounds by using computational proteomic analysis.

The main objective of extracting natural dyes from natural sources is to avoid the environmental pollution. The flower of Tagetes erecta is used for the extraction of dye using alkaline extraction method. There are four different mordants (CuSo4, FeSo4, NaCl, K2Cr2O7) are used in cotton and polyester fabric by simultaneous mordanting method. The dye fixation is carried out at room temperature and also at 100°C. The result revealed that, different shades of yellow, brown and green were obtained from the dye when subjected to mordant. The dye at 100°C showed dark colours and excellent fastness properties when compared to dye fixed at room temperature. The dye extract of Tagetes erecta had a great antimicrobial activity against pathogenic strains of bacteria and fungi and the FT-IR was carried out to identify compounds.

No abstract