Although adhering to the timelines of childhood vaccinations is essential to achieving favorable outcomes, many previous investigations have reported a potential delay in vaccination schedules due to many reasons, including natural disasters, which may have a significant impact on public health, subsequently causing remarkable outbreaks of vaccinationpreventable diseases. The study aim is to assess the impact of the COVID-19 pandemic on routine pediatric vaccination and the associated factors in Saudi Arabia. A systematic review was conducted to identify relevant articles that investigated the impact of the COVID-19 pandemic on pediatric vaccination and the associated factors in Saudi Arabia. A total of three relevant cross-sectional studies were included and was conducted in three different regions: Qassim, Riyadh, and Eastern region. The three studies reported three variable rates for routine vaccination delays of 23.4%, 72.9%, and 33.1%. As for prevalence per childhood vaccination schedules, two studies reported that the highest prevalence rates were reported in two and four month vaccinations, while the third study reported that the highest rates were noticed at 12 and 18 months. Fear of COVID-19 infection was the most common cause of delayed or missed vaccination. Family size, having medical insurance, caregiver age ranges between 18-30 and being a healthcare worker were the most common factors that significantly influenced caregivers to vaccinate their children on time. Further efforts and innovative approaches by healthcare officials are needed to enhance vaccination rates during times of emergency and to implement home visit programs in association with the primary healthcare section.