The FDG-PET is a reasonably accurate and useful tool for characterizing the nature of indeterminate pulmonary lesions, although the specificity was not as high as that reported in the literature, probably owing in part to our patient population and selection bias. Our data suggest that reporting the results of PET studies as a probability rather than as positive or negative for malignancy would be more useful for further management decision making. Correction of SUVs for tumor size did not improve accuracy.
Background. More HIV-infected women are reaching older age and menopause, but there is limited information on cervical squamous intraepithelial lesions (SILs) on these women. Methods. To assess the effect of HAART and menopause on SILs in HIV-infected women, we reviewed the results of Papanicolaou (Pap) tests obtained between 1991 and 2011 on 245 women. Progression to SILs was determined by comparing Pap test results. The association of HAART and transition to menopause on SILs was assessed using survival analysis. Results. Women receiving HAART had a 52% reduced risk in the progression to SILs compared to women receiving any other antiretroviral regimen or no regimen (CI: 0.33–0.70, P = 0.0001). A greater increase of CD4+ cell counts was associated with a greater reduction on the risk of progression to SILs. Menopausal women had a 70% higher risk of progression to SILs than premenopausal women (CI: 1.11–2.62, P < 0.0001), adjusting for HIV medications, CD4+ count, duration of HIV infection, moderation effect of menopause by age, prior IV drug use, and smoking. Conclusion. HAART had a positive long-term effect on the progression to SILs. However, being younger and menopausal increases the risk of progression.
A considerably higher number of adults showed pattern B than pattern C. This suggests that regeneration of diaphyseal marrow precedes that of the distal marrow in an individual long bone or possibly that conversion of the latter precedes the former, which is different from that proposed in the literature.
The more posteriorly located the abnormal focus, the higher the probability of descended SPA. Recognition of the characteristic appearance of descended SPA on SPECT imaging can have a significant impact on the surgical approach and prevent failed neck exploration.
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