Introduction Fibromyalgia syndrome (FMS) is a non-inflammatory, chronic disseminated musculoskeletal pain with unknown etiology. FMS patients suffer from generalized pain that markedly decreases their quality of life and productivity. Objective To investigate the prevalence of FMS and the correlation between people with positive screening criteria for FMS and their socio-demographic characteristics in Taif city. Methodology A cross-sectional study was performed in Taif city, Saudi Arabia, from June 2021 to August 2021. A structured self-estimated electronic questionnaire developed by Google Forms. The questionnaire depended on the 2010 American College of Rheumatology (ACR) criteria. Data analysis was performed by using SPSS, version 21.0 (IBM Corp., Armonk, NY). Result Out of 1015 participants, 77 participants (7.6%) were revealed to have FMS. The prevalence of FMS among females (9.3%) was significantly higher (p<0.001) than that among males (3.1%). In addition, participants aged 40 years old or more showed a significantly higher prevalence of FMS (p=0.003) compared to those aged less than 40 years old (11.7% versus 6.0%, respectively). In addition, occupational status was found to significantly affect FMS prevalence (p=0.040) as the highest prevalence was reported among employees (10.8%) and housewives (9.4%) compared to the unemployed (8.8%), students (5.0%), and retired participants (4.0%). On the other hand, participants’ nationality was shown to have no significant effect on fibromyalgia prevalence (p=0.396). Conclusion Results show a slightly high prevalence rate of FMS in Saudi Arabia. Prevalence was seen greater in women, old age, and employed individuals. Poor knowledge of FMS was seen among the general Saudi population. Educational programs are needed to increase awareness of the disease.

Background With the rising global desire for beauty, cosmetic interventions have increased. Saudi Arabia ranked 29th among the top 30 fastest-growing countries for cosmetic procedures. Objectives This study aims to investigate the prevalence, acceptance level, and health impacts of cosmetic interventions among females in Saudi Arabia. Methods This cross-sectional study was conducted from December 2022 to January 2023 among females living in Saudi Arabia. Participants’ acceptance of cosmetic interventions was assessed using an Arabic version of the validated Acceptance of Cosmetic Surgery Scale (ACSS). Data were collected using a self-administered questionnaire. Results The study included 3007 females living in Saudi Arabia. About 58% of the participants were aged 18 to 25, and 72.9% were single. The prevalence of cosmetic interventions among the participants was 10%. A higher prevalence was observed among participants over 25 years, married, high-economic status, employed, postgraduate, and participants recognizing the necessity of cosmetic interventions (p-value &lt;0.001). High acceptance levels toward cosmetic interventions were observed among older, married, employed, and postgraduate respondents and those with high economic status (p-value &lt; 0.001). Meanwhile, knowing the adverse events of cosmetic interventions was associated with a low level of acceptance with a p-value of &lt;0.001. Conclusions The present study demonstrated a surprising prevalence of cosmetic interventions among females in Saudi Arabia. However, a below-average acceptance of these interventions among the same population was reported. This could be a result of the surrounding culture that does not support or encourage undergoing cosmetic interventions. Further studies are recommended to assess the prevalence of those interventions using objective tools, such as medical records.

Background: Patients with chronic renal disease or failure are at a heightened risk of mortality due to cardiovascular disease (CVD), which is a predominant cause of death in this population. Hyperhomocysteinemia is prevalent in patients with end-stage renal disease (ESRD), which may increase their susceptibility to CVD. Methods: We conducted a comprehensive search of PubMed, Science Direct, and Google Scholar for articles published between 2003 and February 2023, using a combination of keywords such as "plasma homocysteine levels," "hyperhomocysteinemia," "end-stage renal disease," "renal failure," "kidney failure," "cardiovascular events," "cardiovascular disease," "myocardial infarction," "coronary artery disease," and "stroke." Our inclusion criteria were studies that investigated the association between total homocysteine (Hcy) level and CVD or total mortality, as well as the impact of vitamin supplementation on cardiovascular or mortality risk. We restricted our search to English-language studies that included ESRD patients and provided data on plasma Hcy levels and associated CVD events. Results: This systematic review includes 11 articles published between 2003 and 2023 that enrolled a total of 3,953 subjects, of whom 79.15% were male patients. All studies included in the review were either quantitative randomized trials or non-randomized studies, such as cross-sectional, cohort, or case-control studies. Of the total studies included, 10 reported either cardiovascular mortality or CVD events, including cardiovascular death, myocardial infarction (MI), angina, and stroke. One study reported the CVD risk score of the patients, and most of them had higher total homocysteine (tHcy) levels. Overall, a total of 817 CVD events were reported across the studies. Conclusion: In conclusion, the relationship between Hcy and cardiovascular events in ESRD patients is not straightforward and requires further research. However, our review suggests that Hcy could be a predictor of cardiovascular events in this population, and its nutritional characteristics as well as other associated comorbidities may contribute to its inverse association with outcomes.

Background/aimHeart transplantation is often the only preferable treatment for end-stage heart failure (HF); however, there are insufficient organ donors in Saudi Arabia. In this study, we aimed to understand the desire and readiness of Taif populations for heart donation after death. MethodsWe carried out a descriptive cross-sectional study among Taif residents in November 2022. A questionnaire designed from a previous survey was distributed among the participants. The questionnaire included sociodemographic data and questions assessing their desire for heart donation. ResultsThe study included 405 subjects who have accepted to participate in the study. About half of the participants were aged 18 to 32 years (43.5%), most were females, were non-employed, and had a university degree. Of them, 86.2% accepted the concept of organ transplantation, 81% accepted the concept of heart transplantation, and one-third of the participants desired to donate their hearts. The participants with a university degree reported significantly less acceptance of the concept of heart transplantation (p-value=0.026), and those employed showed a significantly stronger desire for organ donation to a relative after death (p-value=0.049). In addition, younger participants showed a significantly higher willingness for organ donation to a relative or non-relative after death (p-value=0.017 and 0.009, respectively). Employed participants were significantly more willing to undergo heart transplantation surgery if needed (p-value=0.044). ConclusionAwareness campaigns could be established in the community and popularized during contact with the health system to build trust in the organ donation system, stress the importance of heart donation in saving the lives of more patients, and reduce the shortage of organ transplantation.