Implantable endovascular devices such as bare metal, drug eluting, and bioresorbable stents have transformed interventional care by providing continuous structural and mechanical support to many peripheral, neural, and coronary arteries affected by blockage. Although effective in achieving immediate restoration of blood flow, the long-term re-endothelialization and inflammation induced by mechanical stents are difficult to diagnose or treat. Here we present nanomaterial designs and integration strategies for the bioresorbable electronic stent with drug-infused functionalized nanoparticles to enable flow sensing, temperature monitoring, data storage, wireless power/data transmission, inflammation suppression, localized drug delivery, and hyperthermia therapy. In vivo and ex vivo animal experiments as well as in vitro cell studies demonstrate the previously unrecognized potential for bioresorbable electronic implants coupled with bioinert therapeutic nanoparticles in the endovascular system.
the diode was consisted of printed inorganic layers of Si and NbSi 2 microparticles with an organic binder. [ 8 ] Because the operational frequency of the diode scales with its charge-transporting properties, the realization of the UHF rectifi er based on organic materials has been a challenge. Recently, a rectifi er with a 3 dB frequency reaching an impressive 700 MHz in terms of voltage was demonstrated, but its voltage output ( V out ) at 1 GHz was only 0.31 V for an AC input signal with 2 V amplitude. [ 9 ] In order to achieve ultrahigh frequency performance organic rectifi ers, which commonly consist of diodes and capacitors, it is important to achieve high charge carrier injection effi ciency and mobility within the organic semiconductor layer. Even if the work function of a metal electrode is selected to match the highest occupied molecular orbital (HOMO) level of an organic semiconductor, the formation of an adversely aligned dipole or other (e.g., oxide) interface layer can lead to a hole injection barrier, limiting charge injection. [ 10,11 ] Self-assembled monolayers (SAMs) represent one good candidate for ensuring effi cient charge injection by specifi cally tuning the metal work function. [12][13][14][15] Interfacial charge trapping can also sometimes help. [ 16 ] The permanent dipole moment of suitably selected SAM molecules changes the effective metal work function, reducing the charge injection barrier. SAMs may also be used to enhance the properties of gate dielectric layers in organic thin fi lm transistors (TFTs). [ 17,18 ] In addition to SAM-based metal work function tuning, surface energy characteristics are also altered by the SAM functional groups. This in turn can modify the subsequent deposition of organic semiconductor layers. In particular, pentacene grain formation, one of the important factors determining pentacene thin fi lm mobility, is much affected by substrate surface energy. The SAM molecule functional groups can be selected to lower the surface energy, thereby enhancing molecular packing and improving mobility. [ 19 ] Studies have shown that the orientation of pentacene deposited on Au is different to that deposited on SAM-treated Au. [20][21][22] The effect that such structural differences have on electrical characteristics for transport in the vertical direction (normal to the fi lm plane) has not been investigated to any great extent; the great majority of studies have focused on in-plane transport within TFT structures. [23][24][25] In this study, we investigated vertical diode structures instead of TFTs and as a result of the understanding gained we were able to fabricate ultrafast pentacene rectifi ers with V out = 3.8 V at 1 GHz and with a 3 dB frequency, in terms of voltage, of 1.24 GHz, the highest value reported to date. [ 8 ] Conjugated organic molecules such as pentacene, demonstrate strong electron-vibrational mode coupling with a dependence on orientation. This allows us to use Raman spectroscopy as a probe for molecular orientation. [ 26 ] Here, For automatic det...
The capsule endoscopy system has been used to obtain an image from the inside of the human digestive tract. To acquire high-resolution images, a loop antenna with ultrawide bandwidth is proposed. It is part of the outer wall of the capsule, thus decreasing volume and increasing performance, and uses a meandered line for resonance in an electrically small area. The proposed antenna makes maximal use of the capsule's outer surface, enabling the antenna to be larger than inner antennas. The measured result shows that the gain of the proposed antenna is higher than that of inner antennas. Return loss and radiation pattern are investigated through simulation and measurement, showing that the proposed antenna has an ultrawide bandwidth of 260 MHz (from 370 to 630 MHz) for VSWR 2 and an omnidirectional radiation pattern. Using identical antenna pairs in the equivalent body phantom fluid, antenna efficiency is measured to 43.7% ( 3.6 dB).Index Terms-Capsule antenna, endoscopy system, loop antenna, meander, small antenna, wideband.
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