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The objective is to study the FSH receptor (FSHR) for mutations in a case of spontaneous ovarian hyperstimulation syndrome (sOHSS). This is a single case study and it examined patient who presented with spontaneous critical OHSS in early pregnancy and had successful good obstetric outcome. Intervention of this study was analysis of blood for genetic analysis of FSHR postdelivery. The main outcome measure noted was FSHR mutation. The study resulted in a novel, here though unreported, heterozygous mutation in FSHR gene at nucleotide position 1346 (AC1346T to AAT) in exon 10 yielding a threonine to asparagine (Thr449Asn) substitution in the transmembrane domain helix 3 of the FSHR. To conclude FSHR gene analysis can add to our understanding of sOHSS.

Helminthic infections such as Strongyloides stercoralis occurs commonly in immunocompromised states. However, they can rarely occur in normal individuals also. A 23 year old multigravida presented at 39 weeks gestation with watery diarrhoea. She was evaluated and diagnosed of strongyloidiasis. Medical management was given and pregnancy outcome was successful. This case is reported because strongyloidiasis is a rare and underreported occurrence in pregnancy, which can occasionally be fatal.

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