Objectives Leucocytospermia is a rare cause of infertility with a variable incidence in infertile men. In many andrology laboratories, semen analysis is primarily centered on analyzing basic parameters (sperm count, motility, and viability). We examined the role of cytomorphological analysis on Papanicolaou (PAP)-stained smears in the work up of male infertility, with special reference to leukocytospermia and assessed the morphological features of sperms in these cases.
Materials and Methods All cases signed out as “leukocytospermia” between November 2017 and January 2018 were evaluated. Cases showing pus cells (≥ 1/5hpf) on cytosmear evaluation were also analyzed. Parameters obtained on modified Neubauer’s chamber, wet mount preparations, and autoanalyzer SQA-IIC-P (Medical Electronic Systems, Israel) were tabulated. PAP-stained smears were examined to assess morphological defects and other findings, if any.
Results Out of 348 semen samples, 6 (1.72%) were diagnosed as leukocytospermia, all displaying pus cells on cytomorphological evaluation. Five cases having white blood cells < 1 × 10 9/L were analyzed, which displayed the presence of pus cells (≥ 1/5 hpf) on cytosmear preparations (1.43%). Nine cases (81.8%) showed reduced motile sperm concentration, functional sperm concentration, and sperm motility index. Morphological evaluation of the PAP-stained smears showed mid-piece defects in 18.1% cases.
Conclusion Diligent cytomorphological evaluation of semen is essential to diagnose leukocytospermia, assess morphological defects, and serve as a quality control measure.
Background: Cervix is vulnerable to many pathological changes ranging from inflammation to malignancy. Cervical polyp is one of the commonest cervical lesion seen in about 2-5% of women. They are more frequent in parous women and are mostly asymptomatic. Symptomatic polyps are frequent in the premenopausal women with most common clinical presentation of AUB(abnormal uterine bleed). Usually they are benign but there are chances of malignant transformation. This study was done to analyse the clinico-pathological spectrum of cervical polyp at a tertiary care institute Methods: A retrospective study was conducted in department of Pathology, BPS GMC for Women Khanpur Kalan, Sonepat over a period of 5 years. All patients who had been diagnosed with cervical polyp clinically and underwent subsequent histopathological sampling were included. Results: A total of 92 cases were included in the study. AUB was the most common clinical presentation of these patients with cervical polyp. Most common age group was 30 to 55 years. Out of 92 cases 47 were of endocervical type polyp, followed by 20 cases of leiomyomatous polypConclusions: To conclude in this study we found that the most common type of cervical polyp is endocervical type. Keeping in view the malignant transformation histopathological sampling of polyp is essential.
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