목적
MRI Dixon method (이하 DIXON) 기법을 이용하여 슬관절 지방우세 골조직의 지방신호분율(fat signal fraction; 이하 FF)을 구하고 골밀도(bone mineral density; 이하 BMD)와 상관관계 분석을 시행하였다.
대상과 방법
본원 슬관절 DIXON 영상을 촬영한 환자들 중 일 년 이내의 dual energy X-ray absorptiometry가 있는 환자 93명을 후향적으로 분석하였다. DIXON 영상에서 원위부 대퇴골 골간단(femur metaphyseal; 이하 Fm)과 근위부 경골 골간단(tibia metaphyseal; 이하 Tm)의 FF를 계산하였다. FF와 BMD 간 상관관계를 분석하였다. 또, 요추(lumbar spine; 이하 L), 대퇴경부(femoral neck; 이하 FN), 총대퇴골(femur total; 이하 FT)의 BMD 별로 나누고 FF에 대하여 Kruskal-Wallis H test를 시행하였다.
결과
전체 환자군에서 TmFF와 FN-BMD 사이에 유의미한 음의 상관관계를 보였다(
r
= -0.26,
p
< 0.05). 여성 환자에서는 TmFF가 FN-BMD, FT-BMD 및 L-BMD와 음의 상관관계를 보였다(
r
= -0.38, -0.28과 -0.27,
p
< 0.05). 남성 환자에서는 FmFF가 FN-BMD 및 FT-BMD와 음의 상관관계를 보였다(
r
= -0.58과
r
= -0.42,
p
< 0.05). 여성 환자들을 세 군으로 나누었을 때 TmFF에 유의한 차이를 보였다(
p
< 0.05). 남성 환자들을 두 군으로 나누었을 때, FmFF이 군 간에 유의미한 차이를 보였다(
p
< 0.05).
결론
슬관절 주변의 FF와 BMD는 음의 상관관계를 보였으며, DIXON을 이용한 FF 측정이 BMD 스크리닝에 사용될 수 있는 가능성을 보였다.
To assess the feasibility and efficacy of an ultrasound needle guidance system (NGS) based on standard needle magnetization in a phantom study in thyroid nodule (TN) targeting puncture.Methods: Six trainees and a staff radiologist performed TN targeting punctures with or without the NGS in phantom models (group 1: experience < 50 cases, group 2: experience ≥ 50 cases and < 100 cases, group 3: experience ≥ 100 cases of TN targeting puncture). The feasibility, technical success rate, number of punctures, and procedure time were recorded.
Results:The feasibility of NGS was 98.6% (138/140). In group 1, the technical success rate was increased from 60.0% ± 8.2% to 80.0% ± 8.2% using the NGS (P = 0.046), with a reduction in the number of punctures from 2.2 to 1.2 (P = 0.005). In group 2, the rate was changed from 95.0% ± 5.8% to 100.0% ± 0.0% with the NGS (P = 0.157), with a minimal decrease in the number of punctures from 1.1 to 1.0 (P = 0.157). The procedure time was significantly decreased in both groups (P = 0.041 and P = 0.010, respectively) with the NGS.In group 3, there were no significant differences in the technical success rate and the number of punctures using the NGS (P = 0.317 and P = 0.317, respectively).
Conclusion: NGS using standard needle magnetization is technically feasible and has potentialto improve the efficacy of TN targeting puncture for less-experienced operators, especially beginners, in a phantom study.
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