Lipoma is called the “universal tumor” or the “ubiquitous tumor” as it occurs anywhere in the body where fat is found. Intraosseous lipoma is a rare lesion that constitutes not more than 0.1% of bone tumors. There are only a few reported cases of intraosseous lipoma of the maxilla in the literature. The diagnosis of intraosseous lipoma of the maxilla may be a challenge, due to its rarity and clinical similarity with many other radiolucent lesions. Therefore, histopathological examination is mandatory. The radiolucent nature and mature adipose tissue admixed with the bony trabeculae confirms the diagnosis of intraosseous lipoma. Here, we report a case of intraosseous lipoma of the left maxillary tuberosity in a 52-year-old male patient.