Many global environmental agendas, including halting biodiversity loss, reversing land degradation, and limiting climate change, depend upon retaining forests with high ecological integrity, yet the scale and degree of forest modification remain poorly quantified and mapped. By integrating data on observed and inferred human pressures and an index of lost connectivity, we generate a globally consistent, continuous index of forest condition as determined by the degree of anthropogenic modification. Globally, only 17.4 million km2 of forest (40.5%) has high landscape-level integrity (mostly found in Canada, Russia, the Amazon, Central Africa, and New Guinea) and only 27% of this area is found in nationally designated protected areas. Of the forest inside protected areas, only 56% has high landscape-level integrity. Ambitious policies that prioritize the retention of forest integrity, especially in the most intact areas, are now urgently needed alongside current efforts aimed at halting deforestation and restoring the integrity of forests globally.

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All possible tools need to be marshalled for marine fish conservation. Yet controversy has swirled around what role, if any, the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) should play for marine fishes. This paper analyses the relevance and applicability of CITES as a complementary tool for fisheries management. CITES currently regulates the international trade of very few marine fish species, by listing them in its Appendices. After the first meeting of the Parties (member countries) in 1976, no new marine fish taxa were added to the CITES Appendices until 2002, when Parties agreed to act to ensure sustainable and legal international trade in seahorses (Hippocampus spp.) and two species of sharks. Progress has continued haltingly, adding only one more shark, humphead wrasse (Cheilinus undulatus) and sawfishes by 2012. Parties voice concerns that may include inadequate data, applicability of CITES listing criteria, roles of national fisheries agencies, enforcement challenges, CITES' lack of experience with marine fishes, and/or identification and by‐catch problems. A common query is the relationship between CITES and other international agreements. Yet all these arguments can be countered, revealing CITES to be a relevant and appropriate instrument for promoting sound marine fisheries management. In reality, Parties that cannot implement CITES effectively for marine fishes will also need help to manage their fisheries sustainably. CITES action complements and supports other international fisheries management measures. As CITES engages with more marine fish listings, there will be greater scope to analyse its effectiveness in supporting different taxa in different contexts.

For over 15-years, proponents of the One Health approach have worked to consistently interweave components that should never have been separated and now more than ever need to be re-connected: the health of humans, non-human animals, and ecosystems. We have failed to heed the warning signs. A One Health approach is paramount in directing our future health in this acutely and irrevocably changed world. COVID-19 has shown us the exorbitant cost of inaction. The time to act is now.

pillover events, in which a pathogen that originates in animals jumps into people, have probably triggered every viral pandemic that's occurred since the start of the twentieth century 1 . What's more, an August 2021 analysis of disease outbreaks over the past four centuries indicates that the yearly probability of pandemics could increase several-fold