<p class="abstract"><strong>Background:</strong> Sexually transmitted diseases (STDs) have been considered as a major health problem, in developing countries like India. Knowledge regarding pattern and prevalence of different STIs is very important to implement proper strategies to control the STDs. The aim of this study is to understand the pattern and prevalence of different sexually transmitted infections (STIs) in eastern Uttar Pradesh.</p><p class="abstract"><strong>Methods:</strong> This is a retrospective observational study. Records of all the patients who had attended the STI clinic from January 2013 to December 2017 in Tertiary care Hospital, Gorakhpur have been analysed.<strong></strong></p><p class="abstract"><strong>Results:</strong> The commonest STD was herpes genitalis 24.04% and condylomata acuminata 23.51% respectively. The prevalence of combined gonococcal/non gonococcal urethritis and bacterial vaginosis accounts for 23.84% and HIV was detected in 13.19% of the patients. There is a decline in occurrence of Syphilis with prevalence of 5.74%.</p><p class="abstract"><strong>Conclusions:</strong> There is increased prevalence of viral STIs and decline in bacterial STIs seen, probably due to easy access of antibiotics to common people.</p>

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Erythrokeratoderma is a rare group of disorders of autosomal dominant inheritance characterised by localised erythema and hyperkeratosis. Within a broad spectrum of phenotypes atleast two are delineated: a) Erythrokeratoderma variabilis and b) Progressive symmetric erythrokeratoderma. Here we are reporting a case of progressive symmetric erythrokeratoderma in an Indian family where five successive generations were involved.