Spindle cell carcinoma (SpCC) is an unusual variant of squamous cell carcinoma (S.C.C.) of the head and neck region. It is a rare biphasic neoplasm. SpCC is an unusual morphological variant of S.C.C. It is characterized by the presence of both carcinomatous as well as sarcomatous component and accounts for 2 to 3% of all the S.C.C.s. Seven years ago, the W.H.O. classification has placed this tumor under the malignant epithelial tumors and called it SpCC. The histogenesis of spindle cells remains controversial and is believed to be monoclonal epithelial neoplasia with a close association with squamous carcinoma cells. Since SpCC is a rare tumor, its histopathological diagnosis is often very complex. Immunohistochemistry (I.H.C.) supports the epithelial nature of this tumor. Both neoplasia components possess immunoreactivity for cytokeratin and vimentin. We are presenting a case of a middle-aged man who was diagnosed with this rare variant at an even rarer location.
Chondroblastoma is a rare benign appearing lesion arising in the epiphysis of long bones in skeletally immature individuals. It is a cartilage-producing neoplasm constituting < 1% of all bone tumors. A 16 years old girl presented to orthopedic OPD of tertiary care hospital with swelling of her left great toe for 3 years. The swelling was insidious at onset and gradually progressed to the present size of 3.5x2.5x2 cm. Radiographic examination shows an osteolytic lesion and coarse trabeculation in the distal phalanx of the great toe suggestive of a benign bone tumor. Histopathological examination showed classical features of chondroblastoma. Post-operative follow-up was uneventful and radiological examination was normal. Flat bones like the pelvis, ribs, vertebrae, scapula, and craniofacial bones are other uncommon locations. The tumor recurrence rate is increased when the tumor is having limited resection due to the site of the tumor. Turcotte et al. reported the highest recurrence rate of tumors in flat temporal bones with recurrence within 6 months to 8 years. Chondroblastoma, an uncommon primary bone tumor presenting at the distal phalanx of the great toe was extremely rare.
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