No abstract

: The coronaviruses belonging to the family Coronaviridae have caused a massive pandemic in December 2019 af-ter its previous outbreaks as SARS-CoV and MERS. The outbreak is believed to have originated from the seafood and live market in Hubei province of China. The Rhinolophus species are the natural hosts of this virus. The unknown virus caus-ing pneumonia took away so many lives before recognising it as the novel Coronavirus. Very little information is known about the biology and nature of the current outbreak. This article reviews multiple aspects encompassing its origin, epide-miology, pathogenesis, symptoms and the global statistics of spread. Acute respiratory distress syndrome (ARDS) is the key symptom of this condition. Angiotensin converting enzyme 2 (ACE2) helps in the penetration of the virus into the tar-get cells. Deeper research and understanding is essential for identification of antibodies that inhibit ACE2 and can prevent viral replication. Drug design and control of disease is crucial. In countries like India where plant diversity is extensive, it is wise to focus on plant based alternative drugs. Many attempts have been made to review and curate the drug discovery attempts using immune-informatics and bioinformatics tools.

This article will throw the light on impact of the global pandemic COVID-19 on the Indian economy including its detailed impact on all the sectors of the economy. The outcome of the study will also highlight the impact of the measures undertaken by the ministry of finance to tackle situations more rationally and set an example and enough basis for the policymakers to make policies for handling the situation in an effective manner.