Sushmitha Ananth scite author profile

Sushmitha Ananth

2Publications

11Citation Statements Received

91Citation Statements Given

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Affiliations

Women's Hospital, Woman’s Hospital of Texas

Publications

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Estrogen exacerbates the nociceptive effects of peripheral serotonin on rat trigeminal sensory neurons

Kaur

McDonald²,

Tongkhuya³

et al. 2021

Neurobiology of Pain

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Highlights 5HT-evoked nocifensive behaviors are sexually dimorphic and dependent on hormone status of the animal. Blocking the excitatory 5HT 2A receptor attenuates 5HT-evoked pain behaviors in females during proestrus/estrus. Basal levels of 5HT are elevated in cycling females as compared to males. Estrogen potentiates serotonergic neuromodulation of capsaicin-evoked CGRP release in female trigeminal sensory neurons.

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(116) Rapid modulatory effects of 17β-estradiol on serotonin’s pronociceptive activity on the TRPV1-expressing population of trigeminal neurons

Lulla

Ananth

Besher

et al. 2017

The Journal of Pain

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