Introduction: Every year millions of people fall sick with Tuberculosis (TB). Multidrug-resistant tuberculosis (MDR-TB) has a life threatening public health crisis globally. Objective: To determine the successful treatment outcomes of MDR-TB in Bangladeshi population. Methods: This retrospective cohort study was conducted at the National Institute of Diseases of the Chest and Hospital (NIDCH) Mohakhali, Dhaka, on 224 patients enrolled within July 2014 to June 2015. Data were collected by face-to-face interview and reviewing medical records. Results: A total of 224 MDR-TB patients’ histories were studied, among them male and female were 71% and 29% respectively. The average age was 37.6± 13.7 years. Of the total MDR-TB patients, 49(21.9%) were successfully treated, 124 (55.4%) had completed, 3(1.3%) had treatment failure, 5(2.2%) were lost to follow-up, 1(0.4%) was XDR-TB and 29 (12.9%) died. This study also found out that the patient with advanced age (≥55;p<0.001), living in rural areas (p<0.01), history of missing dose(p<0.001) and co-morbidity after treatment (p<0.05) were significantly associated with poor treatment outcomes of MDR-TB. Conclusion: The study concluded that the successful treatment outcomes were 77.2% and the mortality rate was 12.9% of MDRTB patients. Living in rural areas and missing dose were significantly associated with poor treatment outcomes. So, the study demonstrated that it is necessary to ensure the completion of whole treatment course to manage TB patients effectively in order to prevent MDR-TB. JAFMC Bangladesh. Vol 18, No 1 (June) 2022: 57-60
Background: Health conditions like Diabetes mellitus sometimes affects serious to health due to unavailability of accurate check. But with advancements of diagnostics test like glycated hemoglobin (HbA1c) can save many lives to detect Diabetes Mellitus. Objective: In this study our main goal is to evaluate the accuracy of glycated hemoglobin (HbA1c.) in the diagnosis of Diabetes Mellitus. Methods: The Tertiary Medical College, Bangladesh, outpatient department (OPD) conducted this cross-sectional study. Where information was gathered between January 2019 and January 2020. During the research, a total of 100 individuals were enrolled with contemporaneous FPG, OGTT and A1c findings and diabetes mellitus suspicion. Purposive sampling was used to acquire the samples according to the inclusion criteria. Results: Most of the patients in the research were aged 47 to 57. 30.8% of the population and the majority (60%) were male. 71% of diabetes patients were identified alone by A1c, followed by 66% by 2h OGTT, and 43% of diabetic patients were diagnosed solely by fasting plasma glucose (FPG). IFG was found in 58% of the patients, whereas OGTT found IGT in 20% of the patients, and A1c found IGT in 24% of the patients. The difference between A1c and OGTT in diagnosing glucose intolerance was statistically significant (P 0.0001). Conclusion: This study's findings support the use of HbA1c as a screening tool for type 2 diabetes. Increasing access to diabetes care in Bangladesh may be made easier by using the HbA1c test, which is less onerous for patients than either FPG or oral glucose tolerance testing.
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